Compositions and methods for stimulating ventilatory and/or respiratory drive
AssigneeCase Western Reserve University
InventorsBenjamin Gaston, Stephen Lewis
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Abstract
A method of stimulating ventilatory and/or respiratory drive in a subject in need thereof includes administering to the subject a therapeutically effective amount of a composition comprising a D-cysteine alkyl ester, adduct thereof, or pharmaceutically acceptable salt, tautomer, or solvate thereof.
Claims20
A method of stimulating ventilatory and/or respiratory drive in a subject in need thereof, the method comprising:
- administering to the subject a therapeutically effective amount of a composition comprising a D-cysteine alkyl ester, adduct thereof, or pharmaceutically acceptable salt, tautomer, or solvate thereof.
A method of reversing at least one of opioid induced respiratory depression in a subject in need thereof, the method comprising:
- administering to the subject a therapeutically effective amount of a composition comprising D-cysteine alkyl ester, adduct thereof, or pharmaceutically acceptable salt, tautomer, or solvate thereof.
The method of 11, wherein the composition is administered to the subject systemically.
A composition comprising:
- an opioid capable of inducing respiratory depression in a subject and an amount of a D-cysteine alkyl ester, adduct thereof, or pharmaceutically acceptable salt, tautomer, or solvate thereof effective to prevent the opioid induced respiratory depression when the composition is administered to the subject.
Dependencies are inferred from the claim text.