Compositions for the management of hyperglycemia and related conditions
AssigneeSami Labs Limited
InventorsMuhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur
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Abstract
Disclosed is a method for therapeutic management of hyperglycemia in mammals using compositions containing thymohydroquinone. More specifically, the invention discloses compositions containing thymohydroquinone for inhibiting the activity of the enzyme α-glucosidase and increasing the cellular uptake of glucose by mammalian cells. The anti-oxidant, anti-inflammatory and anti-glycation effects of thymohydroquinone are also disclosed herein.
Claims6
A method of inhibiting glucosidase enzyme, said method comprising step of bringing into contact glucosidase enzyme with an effective dose of thymohydroquinone or a composition comprising thymohydroquinone standardized to contain about 0.1%-5% w/w thymoquinone, about 0.01%-10% w/w thymohydroquinone, about 20%-95% w/w fatty acids, about 0.001%-3% w/w a-hederin or hederagenin, 0.1%-4.0% w/w rosmarinic acid and 0.2%-2% w/w piperine, the bring about the effect of glucosidase enzyme inhibition.
A method of increasing glucose uptake by mammalian cells, said method comprising steps of bringing into contact mammalian cells with effective dose of thymohydroquinone or a composition comprising thymohydroquinone, standardized to contain about 0.1%-5% w/w thymoquinone, about 0.01%-10% w/w thymohydroquinone, about 20%-95% w/w fatty acids, about 0.001%-3% w/w a-hederin or hederagenin, 0.1%-4.0% w/w rosmarinic acid and 0.2%-2% w/w piperine, to increase glucose uptake by the cells.
A method for the therapeutic management of hyperglycemia and related conditions in mammals, said method comprising steps of administering effective dose of thymohydroquinone or a composition comprising thymohydroquinone, standardized to contain about 0.1%-5% w/w thymoquinone, about 0.01%-10% w/w thymohydroquinone, about 20%-95% w/w fatty acids, about 0.001%-3% w/w a-hederin or hederagenin, 0.1%-4.0% w/w rosmarinic acid and 0.2%-2% w/w piperine to bring about a reduction in the levels of glucose in the blood.
Dependencies are inferred from the claim text.