Methods for treating eye disorders using ocular implants
AssigneeRetina Foundation of the Southwest
InventorKarl Csaky
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Abstract
The present disclosure generally relates to local therapies for the eye and, more particularly, to shaped controlled-release ocular implant devices, including methods for making and using such devices, for delivery of therapeutic agents to the eye. A molded two-layer ocular implant comprises a therapeutic agent for treatment or prevention of a disorder of the eye. The implant comprises a polymer layer and a silicone adhesive layer with a therapeutic agent interspersed therein and joined to the polymer layer. This implant is for placement in the sub-Tenon's space of the eye and provides sustained release of the therapeutic agent during the treatment or prevention of the disorder of the eye.
Claims16
A method of treating an eye disorder in an eye comprising:
- (i) providing a multilayer ocular implant, wherein the ocular implant comprises a therapeutic agent for treatment of the eye disorder;
- and
- (ii) placing the ocular implant into the sub-Tenon's space and in contact with the sclera of the eye;
- wherein the ocular implant comprises a first hardened outer layer comprising a polymer, with the first hardened outer layer comprising curvature at both surfaces, and a second hardened inner layer comprising the therapeutic agent, with the second hardened layer comprising curvature at both surfaces;
- wherein the first hardened layer extends circumferentially beyond the second hardened layer such that the surface of the circumferential extension of the first hardened layer is capable of making contact with the sclera of the eye;
- wherein at least one surface of the second hardened layer is capable of making contact with the sclera of the eye;
- and
- wherein the first hardened layer is resistant to diffusion of the therapeutic agent from the second hardened layer.
Dependencies are inferred from the claim text.