Soft tissue repair allografts and methods for preparing same
AssigneeMusculoskeletal Transplant Foundation
InventorsMichael Locarno, Bryan Choi, Manh-Dan Ngo
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Abstract
Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. One allograft is made from decellularized dermal tissue and constitutes a collagen matrix having substantially uniform density and porosity. Another allograft is a hybrid bilayer tissue form that is made from decellularized dermal and adipose tissues. Methods for making both allografts are also disclosed.
Claims13
An allograft dermal tissue form for use in surgical procedures, comprising a portion of dermal tissue derived from a sample of dermal tissue recovered from a donor and comprising an upper portion of papillary dermis, a lower portion of papillary dermis, and a reticular dermis, wherein the portion of dermal tissue has a first exposed surface formed by a first cut and a second exposed surface formed by a second cut opposite said first exposed surface, said portion of dermal tissue comprising a collagen matrix having uniform density and porosity between said first exposed surface and said second exposed surface, and wherein the portion of dermal tissue comprises at least a portion of the lower portion of papillary dermis and at least a portion of the reticular dermis and essentially lacks an epidermis, a dermis-epidermis junction, the upper portion of papillary dermis and a hypodermis.
Dependencies are inferred from the claim text.