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US 10,881,308 B2Granted
Systems and methods for improving heart-rate variability
AssigneeZiv Healthcare Ltd.
InventorAmos Ziv
Life of this patent
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Abstract
The present invention discloses neuro-stimulation systems and methods for affecting cardiovascular function, particularly for improving heart rate variability and treating arrhythmia.
Claims21
A system comprising:
- a control module;
- at least one neuro-stimulation unit, functionally associated with said control module and configured to generate electrical neuro-stimulation comprising stimulation signals, and
- at least a first electrode and a second electrode, configured to be removably attachable onto skin of a subject, wherein each electrode is electrically connected to one of said at least one neuro-stimulation unit for delivering said stimulation signal to the skin;
- wherein said control module is configured to:
- receive a heart activity signal indicative of temporal heart activity of the subject and to identify reference points in the heart activity signal, thereby obtaining occurrence times of reference points associated with heart beats of the subject, wherein said reference points are indicative of occurrence times of R peaks of heart beats of the subject;
- and
- controllably determine parameters of the stimulation signal generated by said neuro-stimulation unit, including synchronizing the stimulation signal with said occurrence times, wherein said stimulation signal comprises pulses synchronized with said occurrence times of said reference points;
- the system being configured to, at least partially simultaneously:
- apply one of said stimulation signals via said first electrode proximately to an acupoint not associated with cardiovascular function, wherein the acupoint not associated with cardiovascular function is at least one of:
- left Ki6 acupoint, right Ki6 acupoint, left Lv14 acupoint, right Lv14 acupoint, left St32 acupoint, right St32 acupoint, left Lv3 acupoint, and right Lv3 acupoint;
- and
- apply one of said stimulation signals via said second electrode proximately to an acupoint associated with cardiovascular function, wherein the acupoint associated with cardiovascular function is at least one of:
- left Ht7 acupoint, right Ht7 acupoint, left Gb34 acupoint, right Gb34 acupoint, left Ub14 acupoint, right Ub14 acupoint, left Ub15 acupoint, right Ub15 acupoint, left HUA T4 acupoint, right HUA T4 acupoint, left HUA T5 acupoint, and right HUA T5 acupoint,
- thereby increasing heart-rate variability of the subject.
11 more elements
Dependencies are inferred from the claim text.