Spatial optimization for measuring biological analytes

A system for spatial optimization of blood measurements in tissue, the system comprising:

• a processor;
• and
• a memory, the memory communicatively coupled to the processor and storing instructions executable by the processor to perform a method, the method comprising:
• measuring a first Raman signal from the tissue with a probe at a first position;
• calculating a first percentage of a blood component in the first Raman signal;
• moving the probe a predetermined distance to a second position;
• measuring a second Raman signal from the tissue with the probe at the second position;
• calculating a second percentage of the blood component in the second Raman signal;
• moving the probe a predetermined distance to a third position when the second percentage is greater than the first percentage;
• measuring a third Raman signal from the tissue with the probe at the third position;
• calculating a third percentage of the blood component in the third Raman signal;
• moving the probe to the second position when the third percentage is less than the second percentage;
• and
• taking spectral measurements from the second position.

A system for spatial optimization of blood measurements in tissue, the system comprising:

• means for measuring a first Raman signal from the tissue with a probe at a first position;
• means for calculating a first percentage of a blood component in the first Raman signal;
• means for moving the probe a predetermined distance to a second position;
• means for measuring a second Raman signal from the tissue with the probe at the second position;
• means for calculating a second percentage of the blood component in the second Raman signal;
• means for moving the probe a predetermined distance to a third position when the second percentage is greater than the first percentage;
• means for measuring a third Raman signal from the tissue with the probe at the third position;
• means for calculating a third percentage of the blood component in the third Raman signal;
• means for moving the probe to the second position when the third percentage is less than the second percentage;
• and
• means for taking spectral measurements from the second position.