Supplementation of milk formulas with microvesicles isolated from milk
AssigneeHadasit Medical Research Services and Development Ltd.
InventorsShimon Reif, Regina Golan
Life of this patent
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Abstract
Provided are microvesicles isolated from milk, compositions thereof and uses for the preparation of milk formulas. Further provided are microvesicles, including exosomes and/or fat globules which encapsulate various miRNA molecules and uses thereof, as exemplified by supplementing milk formulas.
Claims12
A composition comprising infant formula and microvesicles isolated from skim fraction of natural milk, wherein the microvesicles encapsulate or comprise miRNA molecules, wherein the miRNA molecules comprise miR-148a and miR-6073, wherein the microvesicles further encapsulate or comprise biologically active compounds, and wherein the composition substantially does not include cells present in natural milk.
A method for enriching an infant formula, the method comprising adding an effective amount of microvesicles isolated from skim fraction of natural milk to the infant formula, thereby obtaining an enriched infant formula composition, wherein the infant formula is devoid of animal derived fat, wherein the microvesicles encapsulate or comprise miRNA molecules, wherein the miRNA molecules comprise miR-148a and miR-6073, wherein the microvesicles further encapsulate or comprise biologically active compounds, and wherein the enriched infant formula composition substantially does not include cells present in natural milk.
A method of treating cancer in a subject in need thereof, the method comprising administering a composition comprising milk infant formula and microvesicles isolated from skim fraction of natural milk, wherein the microvesicles encapsulate or comprise miRNA molecules, wherein the miRNA molecules comprise miR-148a and miR-6073, wherein the microvesicles further encapsulate or comprise biologically active compounds, and wherein the composition substantially does not include cells present in natural milk.
Dependencies are inferred from the claim text.