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US 10,870,618 B2Granted
Histone deacetylase inhibitors and uses thereof
AssigneeMUSC Foundation for Research Development
InventorsChung-Jen James Chou, Jesse McClure, Cheng Zhang, Elizabeth Inks
Life of this patent
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Abstract
Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of cancer.
Claims9
A compound according to formula (I):
- wherein:
- R1 is phenyl substituted with —CH2NHC(O)-phenyl, or CH2NHC(O)C═C-phenyl;
- and
- R2 is (i) an alkyl or alkenyl group, optionally substituted with —CF3 or cycloalkyl, or (ii) halo-lower alkyl,
- or a pharmaceutically acceptable salt thereof.
2 more elements
Dependencies are inferred from the claim text.