# US 10,869,978 B2 · Method of CO2 measurement during non-invasive ventilation > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,869,978 B2 - Document ID: US10869978B2 - Status: Granted - Kind: B2 - Application number: 15/780,432 - Filed: 2016-11-24 - Published: 2018-12-20 - Granted: 2020-12-22 - Earliest claimed: 2015-12-02 - Assignees: Koninklijke Philips N.V. - Applicants: Koninklijke Philips N.V. - Inventors: Smita Garde - Web page: https://patentgrep.com/patent/US10869978B2 ## CPC - A61M 16/024: {including calculation means, e.g. using a processor} - A61M 16/0066: {Blowers or centrifugal pumps} - A61M 16/06: Respiratory or anaesthetic masks - A61M 16/08: Bellows; Connecting tubes {(having means for taking samples G01N1/22); Water traps; Patient circuits} - A61M 16/085: {Gas sampling} - A61M 2016/0015: {inhalation detectors} - A61M 2205/505: Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches - A61M 2205/52: with memories providing a history of measured variating parameters of apparatus or patient - A61M 2230/432: partial CO2 pressure (P-CO2) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A method for measuring a patient's expired CO2 level in a non-invasive ventilator system while maintaining a positive inspiratory pressure. The method includes the steps of: receiving, by the non-invasive ventilator system, a signal comprising an instruction to obtain a CO2 measurement from a patient; lowering, by the non-invasive ventilator system in response to the signal, the expiratory positive airway pressure from a first, higher level to a second, lower level for a first time period comprising one or more breaths; obtaining, by a CO2 sensor, a CO2 measurement during the first time period; and returning, after the first time period, the expiratory positive airway pressure to the first, higher level. ## Claims ### Claim 1 A method for measuring a patient's expired CO2 level in a non-invasive ventilator system while maintaining a positive inspiratory pressure, the non-invasive ventilator system comprising a CO2 sensor, the method comprising the steps of: receiving, by the non-invasive ventilator system, a first control signal comprising an instruction to obtain a CO2 measurement from a patient for a user-defined first time period; adjusting, by the non-invasive ventilator system, leak compensation during the user-defined first time period; lowering, by the non-invasive ventilator system in response to the first control signal for the user-defined first time period comprising one or more breaths, (i) an expiratory positive airway pressure from a first, higher level to a second, lower level, and (ii) an inspiratory positive airway pressure of the non-invasive ventilatory system from a third, higher level to a fourth, lower level; obtaining, by the CO2 sensor, a CO2 measurement during the user-defined first time period; and returning, after termination of the user-defined first time period, the expiratory positive airway pressure to the first, higher level and the inspiratory positive airway pressure to the third, higher level. ### Claim 2 (depends on 1) The method of claim 1, wherein the first control signal comprising the instruction to obtain the CO2 measurement from the patient is received from a user. ### Claim 3 (depends on 1) The method of claim 1, wherein the step of lowering the expiratory positive airway pressure from the first, higher level to the second, lower level comprises sending a second control signal to a blower of the non-invasive ventilator. ### Claim 4 (depends on 1) The method of claim 1, further comprising the step of sending the first control signal from a controller of the non-invasive ventilator system to the CO2 sensor, the first control signal comprising instructions to obtain the CO2 measurement during the first time period. ### Claim 5 (depends on 1) The method of claim 1, wherein the second, lower level is approximately 1 cmH2O. ### Claim 6 (depends on 1) The method of claim 1, wherein the user-defined first time period is at least two breaths. ### Claim 7 (depends on 6) The method of claim 6, wherein the user-defined time period is based on a low leak alarm setting of the non-invasive ventilator system. ### Claim 8 (depends on 1) The method of claim 1, wherein the step of receiving further comprises configuring the non-invasive ventilator system to obtain the CO2 measurement at a user-defined periodic interval. ### Claim 9 (depends on 1) The method of claim 1, wherein the CO2 sensor of the non-invasive ventilator system is integrated. ### Claim 10 A non-invasive ventilator configured to measure a patient's expired CO2 level while maintaining a positive inspiratory pressure, the non-invasive ventilator comprising: a user interface configured to receive, from a user, a signal comprising an instruction to obtain a CO2 measurement from the patient during a user-defined first time period comprising-one or more breaths; a CO2 sensor configured to obtain one or more expired CO2 measurements from the patient during the user-defined first time period the one or more expired CO2 measurements including the CO2 measurement; and a controller in communication with the CO2 sensor, the controller configured to: lower, in response to the signal for the user-defined first time period, (i) an expiratory positive airway pressure from a first, higher level to a second, lower level, and (ii) an inspiratory positive airway pressure of the non-invasive ventilatory system from a third, higher level to a fourth, lower level; direct the CO2 sensor to obtain the CO2 measurement during the user-defined first time period; track the one or more breaths; and return, after termination of the user-defined first time period, the expiratory positive airway pressure to the first, higher level and the inspiratory positive airway pressure to the third, higher level. ### Claim 11 (depends on 10) The non-invasive ventilator of claim 10, wherein the controller is configured to lower the expiratory positive airway pressure by controlling an activity of a blower of the non-invasive ventilator. ### Claim 12 (depends on 10) The non-invasive ventilator of claim 10, wherein the CO2 sensor is an integrated sensor located proximate to a patient interface. ### Claim 13 (depends on 10) The non-invasive ventilator of claim 10, wherein the signal further comprises instructions to obtain the CO2 measurement at a user-defined periodic interval during patient-triggered breaths. ### Claim 14 A controller of a non-invasive ventilator system configured to measure a patient's expired CO2 level while maintaining a positive inspiratory pressure, the controller configured to perform steps comprising: receive, from a user interface of the non-invasive ventilator system, a first control signal comprising an instruction to obtain a CO2 measurement from a patient for a user-defined first time period; lower, in response to the first control signal for the user-defined first time period comprising one or more breaths, (i) an expiratory positive airway pressure of the non-invasive ventilator system from a first, higher level to a second, lower level, and (ii) the inspiratory positive airway pressure of the non-invasive ventilator system from a third, higher level to a fourth, lower level, wherein the controller is configured to send a second control signal to a blower of the non-invasive ventilator system; send the first control signal to a CO2 sensor of the non-invasive ventilator system, the first control signal comprising instructions to obtain the CO2 measurement during the user-defined first time period; track the one or more breaths; and return, after termination of the user-defined first time period, the expiratory positive airway pressure to the first, higher level and the inspiratory positive airway pressure to the third, higher level. ### Claim 15 (depends on 14) The controller of claim 14, wherein the second, lower level is approximately 1 cmH2O. ### Claim 16 (depends on 14) The controller of claim 14, wherein the first time period is approximately two breaths.