N-acetylcysteine amide (NAC amide) in the treatment of diseases and conditions associated with oxidative stress
AssigneeSentient Lifesciences, Inc.
InventorGlenn A. Goldstein
Life of this patent
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Abstract
Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human mammalian diseases, disorders, conditions and pathologies. Pharmaceutically or physiologically acceptable compositions of NAC amide or derivatives thereof are administered alone, or in combination with other suitable agents, to reduce, prevent, or counteract oxidative stress and free radical oxidant formation and overproduction in cells and tissues, as well as to provide a new source of glutathione.
Claims15
A dosage form for ophthalmic administration comprising
- (a) a therapeutically effective dose of N-acetylcysteine amide (NAC Amide), or a pharmaceutically acceptable sale or ester thereof;
- and
- (b) an ophthalmically acceptable vehicle or carrier;
- wherein the dosage form comprises about 25 mg to about 500 mg NAC Amide.
A method of treating an ophthalmic disease or condition in a subject in need thereof, wherein the method comprises administering a dosage form for ophthalmic administration, wherein the dosage form comprises:
- (a) a therapeutically effective dose of N-acetylcysteine amide (NAC Amide), or a pharmaceutically acceptable salt or ester thereof;
- and
- (b) an ophthalmically acceptable vehicle or carrier;
- and
- wherein the ophthalmic disease or condition is macular degeneration.
Dependencies are inferred from the claim text.