# US 10,869,818 B2 · Foamable skin composition

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- Number: US 10,869,818 B2
- Document ID: US10869818B2
- Status: Granted
- Kind: B2
- Application number: 16/185,535
- Filed: 2018-11-09
- Published: 2019-05-16
- Granted: 2020-12-22
- Earliest claimed: 2017-11-10
- Assignees: Paragon Nordic AB
- Applicants: Paragon Nordic AB
- Inventors: Marie Hedrén; Malin Burstedt
- Web page: https://patentgrep.com/patent/US10869818B2

## CPC

- A61K 8/046: {Aerosols; Foams}
- A61K 8/062: {Oil-in-water emulsions}
- A61K 8/31: Hydrocarbons
- A61K 8/342: {Alcohols having more than seven atoms in an unbroken chain}
- A61K 8/361: {Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof}
- A61K 8/37: Esters of carboxylic acids
- A61K 8/375: {the alcohol moiety containing more than one hydroxy group}
- A61K 8/39: Derivatives containing from 2 to 10 oxyalkylene groups
- A61K 8/4973: {with oxygen as the only hetero atom}
- A61Q 19/00: Preparations for care of the skin
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A foamable skin composition comprises, in % by weight of the foamable skin composition, at least one C12-C22 fatty acid at a concentration of 1-3%, at least one C12-C22 fatty alcohol at a concentration of 1-5%, at least one ester and/or vegetable oil at a concentration of 1-40%, at least one non-ionic surfactant at a concentration of 1-15%, at least one emollient at a concentration of 0.5-10% and water. The foamable skin composition has an acidic pH but still forms a stable form following dispensing.

## Claims

### Claim 1

A foamable skin composition comprising:
at least one C12-C22 fatty acid at a concentration of 1-3% by weight of said foamable skin composition;
at least one C12-C22 fatty alcohol at a concentration of 1-5% by weight of said foamable skin composition;
at least one ester at a concentration of 1-40% by weight of said foamable skin composition, wherein said at least one ester is a mixture of caprylic triglyceride, capric triglyceride, diisopropyl adipate, butylene glycol dicaprylate and butylene glycol dicaprate;
at least one non-ionic surfactant at a concentration of 1-15% by weight of said foamable skin composition;
at least one emollient at a concentration of 0.5-10% by weight of said foamable skin composition; and
water, wherein said foamable skin composition has an acidic pH.

### Claim 2 (depends on 1)

The foamable skin composition according to claim 1, further comprising at least one propellant.

### Claim 3 (depends on 1)

The foamable skin composition according to claim 1, wherein
said at least one C12-C22 fatty acid is at least one C12-C18 fatty acid; and
said at least one C12-C22 fatty alcohol is a C12-C18 fatty alcohol.

### Claim 4 (depends on 3)

The foamable skin composition according to claim 3, wherein
said at least one C12-C18 fatty acid is selected from the group consisting of lauric acid, myristic acid, palmitic acid, stearic acid, myristoleic acid, palmitoleic acid, sapienic acid, oleic acid, elaidic acid, vaccenic acid, linoleic acid, linoelaidic acid and a mixture thereof; and
said at least one C12-C18 fatty alcohol is selected from the group consisting of cetearyl alcohol, cetyl alcohol, myristyl alcohol, stearyl alcohol and a mixture thereof.

### Claim 5 (depends on 1)

The foamable skin composition according to claim 1, wherein said at least one C12-C22 fatty acid is at a concentration of 1.5-2.5% by weight of said foamable skin composition.

### Claim 6 (depends on 1)

The foamable skin composition according to claim 1, wherein said at least one C12-C22 fatty alcohol is at a concentration of 1-4% by weight of said foamable skin composition.

### Claim 7 (depends on 1)

The foamable skin composition according to claim 1, wherein said at least one non-ionic surfactant is selected from the group consisting of sorbitan laurate, polyglycerol-4 laurate, polyglycerol-4 succinate, polysorbate and a mixture thereof.

### Claim 8 (depends on 1)

The foamable skin composition according to claim 1, wherein said at least one non-ionic surfactant is at a concentration of 2-8% by weight of said foamable skin composition.

### Claim 9 (depends on 1)

The foamable skin composition according to claim 1, further comprising at least one vegetable oil at a concentration of 1-40% by weight of said foamable skin composition.

### Claim 10 (depends on 9)

The foamable skin composition according to claim 9, wherein said at least one vegetable oil is selected from the group consisting of sesame oil, olive oil, almond oil, apricot kernel oil, avocado oil, evening primrose oil, grapeseed oil, hazelnut oil, jojoba oil, pumpkin oil, rosehip oil, safflower oil, walnut oil, wheatgerm oil, sunflower oil, and a mixture thereof.

### Claim 11 (depends on 1)

The foamable skin composition according to claim 1, wherein said at least one ester is at a concentration of 1-20% by weight of said foamable skin composition.

### Claim 12 (depends on 1)

The foamable skin composition according to claim 1, wherein said at least one emollient is selected from the group consisting of squalane, isodecyl neopentanoate, dimethicone, paraffinum liquidum, diethylhexyl maleate, diethylhexyl malate and a mixture thereof.

### Claim 13 (depends on 1)

The foamable skin composition according to claim 1, wherein said at least one emollient is at a concentration of 1-8% by weight of said foamable skin composition.

### Claim 14 (depends on 1)

The foamable skin composition according to claim 1, further comprising at least one humectant at a concentration of 1-40% by weight of said foamable skin composition.

### Claim 15 (depends on 14)

The foamable skin composition according to claim 14, wherein said at least one humectant is selected from the group consisting of 1,3-propanediol, glycerol, urea, betaine and a mixture thereof.

### Claim 16 (depends on 14)

The foamable skin composition according to claim 14, wherein said at least one humectant is at a concentration of 1-30% by weight of said foamable skin composition.

### Claim 17 (depends on 1)

The foamable skin composition according to claim 1, further comprising at least one pH adjuster at a concentration sufficient to achieve an acidic pH of said foamable skin composition.

### Claim 18 (depends on 1)

The foamable skin composition according to claim 1, wherein said foamable skin composition has a pH of 3-6.

### Claim 19 (depends on 1)

The foamable skin composition according to claim 1, wherein said foamable skin composition has a foam density of at least 50%, wherein said foam density is defined as 100×H1/H0%, H0 represents height of a foam directly after dispensing said foamable skin composition to form said foam and H0 represents height of said foam 1 minute after dispensing said foamable skin composition.

### Claim 20 (depends on 1)

The foamable skin composition according to claim 1, wherein a foam formed by dispensing said foamable skin composition has a density within an interval of from 20 mg/ml up to 60 mg/ml.

### Claim 21

A foamable skin composition, comprising:
a mixture of stearic acid and palmitic at a concentration of 1-3% by weight of said foamable skin composition;
cetearyl alcohol at a concentration of 1-5% by weight of said foamable skin composition;
a mixture of caprylic triglyceride, capric triglyceride, diisopropyl adipate, butylene glycol diaprylate and butylene glycol dicaprate at a concentration of 1-40% by weight of said foamable skin composition;
a mixture of sorbitan laurate, polyglycerol-4 laurate and polyglycerol-4 succinate at a concentration of 1-15% by weight of said foamable skin composition;
squalene at a concentration of 0.5-5% by weight of said foamable skin composition; and
water, wherein said foamable skin composition has an acidic pH.

### Claim 22 (depends on 21)

The foamable skin composition according to claim 21, comprising:
said mixture of stearic acid and palmitic acid at a concentration of 2% by weight of said foamable skin composition;
cetearyl alcohol at a concentration of 2% by weight of said foamable skin composition;
diisopropyl adipate at a concentration of 2.5% by weight of said foamable skin composition;
a mixture of caprylic triglyceride and capric triglyceride at a concentration of 2.5% by weight of said foamable skin composition;
a mixture of butylene glycol dicaprylate and butylene glycol dicaprate at a concentration of 2% by weight of said foamable skin composition;
1,3-propanediol at a concentration of 4 or 5% by weight of said foamable skin composition;
sorbitan laurate at a concentration of 2% by weight of said foamable skin composition;
a mixture of polyglycerol-4 laurate and polyglycerol-4 succinate at a concentration of 2.9% by weight of said foamable skin composition;
squalane at a concentration of 2% by weight of said foamable skin composition; and
water.

### Claim 23 (depends on 1)

A method of producing a foamable skin composition according to claim 1, said method comprising:
a) mixing and heating water and at least one C12-C22 fatty acid at a concentration of 1-3% by weight of said foamable skin composition until said at least one C12-C22 fatty acid melts to form a water mixture;
b) mixing and heating at least one C12-C22 fatty alcohol at a concentration of 1-5% by weight of said foamable skin composition and at least one ester at a concentration of 1-40% by weight of said foamable skin composition, at least one pre-warmed non-ionic surfactant at a concentration of 1-15% by weight of said foamable skin composition, and at least one emollient at a concentration of 0.5-10% by weight of said foamable skin composition to form an oil mixture;
c) mixing said water mixture and said oil mixture; and
d) optionally adjusting the pH of said foamable skin composition to achieve an acidic pH, wherein said foamable skin composition has an acidic pH and wherein said at least one ester is a mixture of caprylic triglyceride, capric triglyceride, diisopropyl adipate, butylene glycol dicaprylate and butylene glycol dicaprate.
