# US 10,869,780 B2 · Optimization of spherical aberration parameters for corneal laser treatment

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- Number: US 10,869,780 B2
- Document ID: US10869780B2
- Status: Granted
- Kind: B2
- Application number: 15/735,724
- Filed: 2017-02-10
- Published: 2020-01-23
- Granted: 2020-12-22
- Earliest claimed: 2017-02-10
- Assignees: Alcon Inc.
- Applicants: Novartis AG
- Inventors: Sissimos Lemonis
- Web page: https://patentgrep.com/patent/US10869780B2

## CPC

- A61F 9/008: using laser
- A61F 9/00838: {Correction of presbyopia}
- A61F 9/00808: {Inducing higher orders, e.g. for correction of presbyopia}
- A61B 3/112: {for measuring diameter of pupils}
- A61F 2009/00872: {Cornea}
- A61F 2009/00878: {Planning}
- A61F 2009/00895: {Presbyopia}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A method for determining spherical aberration parameters for a corneal laser treatment to treat presbyopia may include performing pupillometry to measure various actual pupil diameters of a patient from a photopic diameter to a mesopic diameter. An actual pupil center of the patient may also be measured. The measured pupil diameters and the pupil center may be used to customize the spherical aberration parameters to the eye of the patient for improved ocular results after treatment.

## Claims

### Claim 1

A method for optimization of spherical aberration parameters for corneal laser treatments, the method comprising:
performing pupillometry on a patient subject to a corneal laser treatment to measure respective pupil diameters including: a mesopic diameter, a normal indoor light diameter, an accommodative reading diameter, and a photopic diameter;
calculating an outer diameter for the spherical aberration that is greater than the mesopic diameter;
calculating an inner diameter for the spherical aberration associated with an amplitude of the spherical aberration that corresponds to the photopic diameter;
calculating the amplitude of the spherical aberration according to a refraction that induces myopia;
calculating a slope of the spherical aberration extending from the photopic diameter to the normal indoor light diameter to provide optimized spherical aberration over a pupil area extending from the measured accommodative reading diameter to the measured photopic diameter; and
using the spherical aberration calculated, including the outer diameter, the inner diameter, the amplitude, and the slope, performing the corneal laser treatment on the patient.

### Claim 2 (depends on 1)

The method of claim 1 wherein the spherical aberration is myopic over a pupil area extending from the pupil center to the measured accommodative reading diameter.

### Claim 3 (depends on 2)

The method of claim 2 wherein the spherical aberration is emmetropic over a pupil area extending from the measured accommodative reading diameter to the measured mesopic pupil diameter.

### Claim 4 (depends on 1)

The method of claim 1, wherein performing the pupillometry further comprises determining a pupil center of the pupil, and further comprising:
calculating a center of the spherical aberration based on the pupil center.

### Claim 5 (depends on 1)

The method of claim 1, wherein the corneal laser treatment is a presbyopia treatment.

### Claim 6 (depends on 1)

The method of claim 1, wherein the corneal laser treatment is performed using a laser-assisted in situ keratomileusis (LASIK).

### Claim 7 (depends on 1)

The method of claim 1, wherein calculating the slope of the spherical aberrations includes adding higher-order spherical aberrations.

### Claim 8

A laser parameter system for optimization of spherical aberration parameters for corneal laser treatments, the system comprising:
a processor having access to memory media storing instructions executable by the processor to:
receive pupillometry data for a patient subject to a corneal laser treatment, the pupillometry data comprising respective pupil diameters including: a mesopic diameter, a normal indoor light diameter, an accommodative reading diameter, and a photopic diameter;
calculate an outer diameter for the spherical aberration that is greater than the mesopic diameter;
calculate an inner diameter for the spherical aberration associated with an amplitude of the spherical aberration that corresponds to the photopic diameter;
calculate the amplitude of the spherical aberration according to a refraction that induces myopia;
calculate a slope of the spherical aberration extending from the photopic diameter to the normal indoor light diameter to provide optimized spherical aberration over a pupil area extending from the measured accommodative reading diameter to the measured photopic diameter; and
using the spherical aberration calculated, including the outer diameter, the inner diameter, the amplitude, and the slope, cause the corneal laser treatment to be performed on the patient.

### Claim 9 (depends on 8)

The laser parameter system of claim 8 wherein the spherical aberration is myopic over a pupil area extending from the pupil center to the measured accommodative reading diameter.

### Claim 10 (depends on 9)

The laser parameter system of claim 9 wherein the spherical aberration is emmetropic over a pupil area extending from the measured accommodative reading diameter to the measured mesopic pupil diameter.

### Claim 11 (depends on 8)

The laser parameter system of claim 8, wherein the pupillometry data further comprise a pupil center of the pupil, and wherein the instructions are further executable to:
calculate a center of the spherical aberration based on the pupil center.

### Claim 12 (depends on 8)

The laser parameter system of claim 8, wherein the corneal laser treatment is a presbyopia treatment.

### Claim 13 (depends on 8)

The laser parameter system of claim 8, wherein the corneal laser treatment is performed using a laser-assisted in situ keratomileusis (LASIK).

### Claim 14 (depends on 8)

The laser parameter system of claim 8, wherein the instructions to calculate the slope of the spherical aberrations include instructions to add higher-order spherical aberrations.