# US 10,869,758 B2 · Systems and methods for heart valve therapy > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,869,758 B2 - Document ID: US10869758B2 - Status: Granted - Kind: B2 - Application number: 15/889,576 - Filed: 2018-02-06 - Published: 2018-08-09 - Granted: 2020-12-22 - Earliest claimed: 2017-02-06 - Assignees: Caisson Interventional, LLC - Applicants: Caisson Interventional, LLC - Inventors: Kavitha Ganesan; Ramji T. Iyer; Todd J. Mortier; Cyril J. Schweich, Jr.; Benjamin L. Montag; Steven N. Willard - Web page: https://patentgrep.com/patent/US10869758B2 ## CPC - A61F 2/2418: {Scaffolds therefor, e.g. support stents} - A61F 2/2409: {Support rings therefor, e.g. for connecting valves to tissue (annuloplasty rings A61F2/2442)} - A61F 2/2433: {using balloon catheter} - A61F 2/2436: {Deployment by retracting a sheath} - A61F 2/2439: {Expansion controlled by filaments} - A61F 2/2454: {Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses} - A61F 2/246: {Devices for obstructing a leak through a native valve in a closed condition} - A61F 2/2466: {Delivery devices therefor} - A61F 2210/0014: using shape memory or superelastic materials, e.g. nitinol - A61F 2220/0008: Fixation appliances for connecting prostheses to the body - A61F 2230/0034: D-shaped - A61F 2230/0093: Umbrella-shaped, e.g. mushroom-shaped - A61F 2250/006: modular - A61F 2250/0098: radio-opaque, e.g. radio-opaque markers - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Some embodiments of prosthetic valves described herein include an anchor portion that couples to the anatomy near a native valve, and a valve portion that is mateable with the anchor portion. In some such embodiments, the anchor portion and/or the deployment system includes one or more prosthetic elements that temporarily augment or replace the sealing function of the native valve leaflets. ## Claims ### Claim 1 A prosthetic mitral valve system comprising: an anchor assembly comprising an expandable anchor frame and a prosthetic element attached to the expandable anchor frame, the anchor assembly coupleable with a native mitral valve having an anterior leaflet and a posterior leaflet that cycle between an open valve orientation and a closed valve orientation in which free edges of the anterior and posterior leaflets oppose each other to define a coaptation line, wherein while the anchor assembly is coupled with the native mitral valve: (i) the anterior and posterior leaflets continue to cycle between the open valve orientation and the closed valve orientation in which the free edges of the anterior and posterior leaflets oppose each other to define the coaptation line, (ii) at least a portion of the prosthetic element is positioned along the coaptation line between the free edges of the anterior and posterior leaflets while the anterior and posterior leaflets are in the closed valve orientation and (iii) the prosthetic element functions as a prosthetic leaflet that cycles between the open valve orientation and the closed valve orientation; and a valve assembly comprising an expandable valve frame and an occluder attached to the expandable valve frame, the valve assembly selectively coupleable with the anchor assembly. ### Claim 2 (depends on 1) The prosthetic mitral valve system of claim 1, wherein the prosthetic element is configured to function as a prosthetic posterior leaflet while the anchor assembly is coupled with the native mitral valve. ### Claim 3 (depends on 2) The prosthetic mitral valve system of claim 2, wherein the prosthetic element comprises a single, continuous member. ### Claim 4 (depends on 2) The prosthetic mitral valve system of claim 2, wherein the prosthetic element comprises multiple members that are not directly connected to each other. ### Claim 5 (depends on 2) The prosthetic mitral valve system of claim 2, wherein the prosthetic element comprises three members that are not directly connected to each other. ### Claim 6 (depends on 1) The prosthetic mitral valve system of claim 1, wherein the prosthetic element comprises flexible, sheet-like material. ### Claim 7 (depends on 1) The prosthetic mitral valve system of claim 1, wherein the prosthetic element is attached to a portion of the expandable anchor frame that is positioned superior to an annulus of the native mitral valve while the anchor assembly is coupled with the native mitral valve. ### Claim 8 (depends on 7) The prosthetic mitral valve system of claim 7, further comprising one or more tethers attached to the prosthetic element and to a portion of the expandable anchor frame that is positioned inferior to the annulus of the native mitral valve while the anchor assembly is coupled with the native mitral valve. ### Claim 9 (depends on 1) The prosthetic mitral valve system of claim 1, wherein the prosthetic element comprises two or more separate members that are attached to the anchor assembly in a fully-circumferential arrangement. ### Claim 10 (depends on 9) The prosthetic mitral valve system of claim 9, wherein the prosthetic element comprises: a first prosthetic element configured to function as a prosthetic posterior leaflet while the anchor assembly is coupled with the native mitral valve; and a second prosthetic element configured to function as a prosthetic anterior leaflet while the anchor assembly is coupled with the native mitral valve. ### Claim 11 (depends on 9) The prosthetic mitral valve system of claim 9, wherein the prosthetic element comprises three separate prosthetic elements.