# US 10,869,757 B2 · Valve prosthesis and method for delivery > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,869,757 B2 - Document ID: US10869757B2 - Status: Granted - Kind: B2 - Application number: 15/831,588 - Filed: 2017-12-05 - Published: 2018-04-26 - Granted: 2020-12-22 - Earliest claimed: 2013-01-08 - Assignees: Medtronic, Inc. - Applicants: Medtronic, Inc. - Inventors: Igor Kovalsky; Jason Quill; Daniel Glozman; Ilia Hariton; Yossi Tuval; Nadav Yellin - Web page: https://patentgrep.com/patent/US10869757B2 ## CPC - A61F 2/2418: {Scaffolds therefor, e.g. support stents} - A61F 2/2412: {with soft flexible valve members, e.g. tissue valves shaped like natural valves} - A61F 2/2454: {Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses} - A61F 2/2457: {Chordae tendineae prostheses} - A61F 2220/0008: Fixation appliances for connecting prostheses to the body - A61F 2220/0016: with sharp anchoring protrusions, e.g. barbs, pins, spikes - A61F 2220/0075: sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable - A61F 2230/0008: elliptical or oval - A61F 2230/001: Figure-8-shaped, e.g. hourglass-shaped - A61F 2230/005: Rosette-shaped, e.g. star-shaped - A61F 2230/0054: V-shaped - A61F 2230/0078: hyperboloidal - A61F 2230/008: paraboloidal - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened. ## Claims ### Claim 1 A valve prosthesis comprising: a frame including a central portion, a support member extending from the central portion, the support member including a leaflet engagement portion configured to engage a native valve leaflet and a chordae engagement portion configured to engage and tension at least one native chorda to thereby restrict movement of the valve prosthesis in an upstream direction of blood flow, wherein an outflow end of the leaflet engagement portion is laterally offset from an outflow end of the chordae engagement portion, and an inlet portion extending radially outward from the central portion and configured to engage a floor of an outflow tract of a native heart atrium to thereby restrict movement of the valve prosthesis in a downstream direction of blood flow; and a prosthetic valve secured to the central portion. ### Claim 2 (depends on 1) The valve prosthesis of claim 1, wherein the support member and the inlet portion act in opposition to create a seal between the inlet portion and a floor of an outflow tract of a native heart atrium after implantation of the valve prosthesis. ### Claim 3 (depends on 2) The valve prosthesis of claim 2, wherein the seal is maintained throughout a cardiac cycle of a patient. ### Claim 4 (depends on 2) The valve prosthesis of claim 2, wherein the seal is maintained during changes in chordal tension throughout a cardiac cycle of a patient. ### Claim 5 (depends on 1) The valve prosthesis of claim 1, wherein at least a portion of the inlet portion has a flexibility of between 0.8 N/m to 2 N/m. ### Claim 6 (depends on 1) The valve prosthesis of claim 1, wherein a cross-section of the inlet portion is substantially s-shaped. ### Claim 7 (depends on 1) The valve prosthesis of claim 1, wherein at least a portion of the frame is self-expandable. ### Claim 8 (depends on 1) The valve prosthesis of claim 1, wherein at least a portion of the frame is balloon-expandable. ### Claim 9 (depends on 1) The valve prosthesis of claim 1, wherein the support member of the frame comprises multiple support members. ### Claim 10 (depends on 9) The valve prosthesis of claim 9, wherein each support member comprises at least one engagement portion configured to engage and tension at least one native chorda to thereby restrict movement of the valve prosthesis in an upstream direction of blood flow. ### Claim 11 (depends on 1) The valve prosthesis of claim 1, wherein the inlet portion is configured to deform a floor of an outflow tract of a native heart atrium. ### Claim 12 (depends on 1) The valve prosthesis of claim 1, wherein the inlet portion is configured to engage an atrial wall. ### Claim 13 (depends on 1) The valve prosthesis of claim 1, wherein the central portion is configured to conform to a native annulus. ### Claim 14 (depends on 1) The valve prosthesis of claim 1, wherein the central portion has an hourglass-shape. ### Claim 15 (depends on 1) The valve prosthesis of claim 1, wherein the chordae engagement portion is configured to angle the at least one native chorda so that the at least one native chorda is stretched. ### Claim 16 (depends on 1) The valve prosthesis of claim 1, wherein the leaflet engagement portion is a support arm having a first end directly attached to the central portion and a second end directly attached to the central portion. ### Claim 17 (depends on 16) The valve prosthesis of claim 16, wherein the chordae engagement portion has a first end directly attached to the support arm and a second end directly attached to the support arm. ### Claim 18 (depends on 16) The valve prosthesis of claim 16, wherein the chordae engagement portion has a first end directly attached to the support arm and a second end directly attached to the central portion. ### Claim 19 (depends on 16) The valve prosthesis of claim 16, wherein the chordae engagement portion has a first end directly attached to the central portion and a second end directly attached to the central portion. ### Claim 20 (depends on 1) The valve prosthesis of claim 1, wherein the outflow end of the leaflet engagement portion is also longitudinally offset from the outflow end of the chordae engagement portion.