# US 10,869,611 B2 · Motion tracking system for real time adaptive imaging and spectroscopy

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- Number: US 10,869,611 B2
- Document ID: US10869611B2
- Status: Granted
- Kind: B2
- Application number: 15/837,240
- Filed: 2017-12-11
- Published: 2018-09-06
- Granted: 2020-12-22
- Earliest claimed: 2006-05-19
- Assignees: The Queen's Medical Center; University of Hawaii; The Medical Collene of Wisconsin, Inc.; UWM Research Foundation, Inc.
- Applicants: The Queen's Medical Center; The University of Hawaii; The Medical College of Wisconsin, Inc.; Uwm Research Foundation, Inc.
- Inventors: Thomas Michael Ernst; Thomas Edmund Prieto; Brian Stewart Randall Armstrong
- Web page: https://patentgrep.com/patent/US10869611B2

## CPC

- A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
- A61B 5/0077: {Devices for viewing the surface of the body, e.g. camera, magnifying lens}
- A61B 5/1127: {using markers}
- A61B 5/1128: {using image analysis (A61B5/1127 takes precedence)}
- A61B 5/721: {using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured}
- A61B 5/7292: {Prospective gating, i.e. predicting the occurrence of a physiological event for use as a synchronisation signal}
- A61B 6/0492: {using markers or indicia for aiding patient positioning}
- A61B 6/547: {involving tracking of position of the device or parts of the device}
- G01R 33/28: Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R 33/56509: {due to motion, displacement or flow, e.g. gradient moment nulling (G01R33/567 takes precedence)}
- G06T 7/0012: {Biomedical image inspection}
- G06T 7/70: Determining position or orientation of objects or cameras (camera calibration G06T7/80)
- H04N 7/18: Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
- G06V 10/62: relating to a temporal dimension, e.g. time-based feature extraction; Pattern tracking
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- H04N: PICTORIAL COMMUNICATION, e.g. TELEVISION
- G06V: IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING

## Abstract

This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time.

## Claims

### Claim 1

A motion tracking system for an object in a magnetic resonance imaging scanner, the system comprising:
an optical landmark on the object;
at least two detectors configured to periodically image the optical landmark, the at least two detectors each configured to view the optical landmark along a different line of sight; and
a tracking system configured to analyze images generated by the at least two detectors to determine changes in position of the optical landmark, to generate tracking data for use by the magnetic resonance imaging scanner to dynamically adjust scans to compensate for the changes in position of the optical landmark, and to store the tracking data for processing;
wherein the tracking system comprises a computer processor and an electronic memory.

### Claim 2 (depends on 1)

The motion tracking system of claim 1, wherein the tracking system is further configured to predict changes in position of the optical landmark by analyzing a plurality of previously determined changes in position of the optical landmark.

### Claim 3 (depends on 1)

The motion tracking system of claim 1, wherein each of the at least two detectors comprises a camera.

### Claim 4 (depends on 1)

The motion tracking system of claim 1, wherein the optical landmark indicates orientation in at least three degrees of freedom.

### Claim 5 (depends on 1)

The motion tracking system of claim 1, wherein the optical landmark is an RGR tag.

### Claim 6 (depends on 1)

The motion tracking system of claim 1, wherein the optical landmark is affixed to the object.

### Claim 7 (depends on 1)

The motion tracking system of claim 1, wherein at least one of the at least two detectors is configured to be positioned within the magnetic resonance imaging scanner.

### Claim 8 (depends on 1)

The motion tracking system of claim 1, wherein each of the at least two detectors is configured to be positioned within the magnetic resonance imaging scanner.

### Claim 9 (depends on 1)

The motion tracking system of claim 1, further comprising at least one mirror configured to provide an indirect line of sight between the optical landmark and at least one of the at least two detectors.

### Claim 10 (depends on 1)

The motion tracking system of claim 1, wherein the at least two detectors are configured to be positioned to enable at least one detector to view the optical landmark when the sight line from another detector to the optical landmark is obstructed.

### Claim 11

A motion tracking system for an object in a medical imaging scanner, the system comprising:
an optical landmark on the object;
a detector configured to periodically image the optical landmark, the detector configured to be positioned within the medical imaging scanner; and
a tracking system configured to analyze images generated by the detector to determine changes in position of the optical landmark, and to generate tracking data for use by the medical imaging scanner to dynamically adjust scans to compensate for the changes in position of the optical landmark, and to store the tracking data for processing,
wherein the tracking system comprises a computer processor and an electronic memory.

### Claim 12 (depends on 11)

The motion tracking system of claim 11, wherein the medical imaging scanner comprises a computer tomography (CT) scanner, an MR scanner, a PET scanner, a SPECT scanner, or a digital angiographic scanner.

### Claim 13 (depends on 11)

The motion tracking system of claim 11, wherein the tracking system is configured to analyze images generated by the detector to determine changes in position of the optical landmark and to automatically calibrate the tracking system.

### Claim 14 (depends on 11)

The motion tracking system of claim 11, wherein the detector is a camera.

### Claim 15 (depends on 11)

The motion tracking system of claim 11, wherein the optical landmark is an RGR tag.

### Claim 16 (depends on 11)

The motion tracking system of claim 11, wherein the optical landmark indicates orientation is at least three degrees of freedom.

### Claim 17 (depends on 11)

The motion tracking system of claim 11, wherein the optical landmark is affixed to the object.

### Claim 18 (depends on 11)

The motion tracking system of claim 11, wherein the detector is configured to be positioned within the medical imaging scanner.

### Claim 19 (depends on 18)

The motion tracking system of claim 18, wherein the medical imaging scanner comprises a computer tomography (CT) scanner, an MR scanner, a PET scanner, a SPECT scanner, or a digital angiographic scanner.

### Claim 20 (depends on 11)

The motion tracking system of claim 11, further comprising a first mirror configured to split a sight line of the detector into a first path and a second path;
wherein the first path is directed directly at the optical landmark;
wherein the second path is directed toward a second mirror; and
wherein the second mirror is configured to deflect the second path toward the optical landmark.
