# US 10,869,476 B2 · Use of Pydiflumetofen for the reduction of mycotoxin contamination in plants

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- Number: US 10,869,476 B2
- Document ID: US10869476B2
- Status: Granted
- Kind: B2
- Application number: 15/766,726
- Filed: 2016-10-07
- Published: 2018-10-04
- Granted: 2020-12-22
- Earliest claimed: 2015-10-09
- Assignees: Bayer CropScience AG
- Applicants: Bayer Cropscience Aktiengesellschaft
- Inventors: Peter Dahmen; Pierre-Yves Coqueron; Ingo Wetcholowsky
- Web page: https://patentgrep.com/patent/US10869476B2

## CPC

- A01N 43/56: 1,2-Diazoles; Hydrogenated 1,2-diazoles
- C07D 233/56: with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- A01C 1/06: Coating or dressing seed
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A01C: PLANTING; SOWING; FERTILISING (parts, details or accessories of agricultural machines or implements, in general A01B51/00 - A01B75/00)

## Abstract

The present invention relates to the novel use of the pyrazole carboxylic acid amide derivative Pydiflumetofen, compositions comprising this compound and its use in methods for the reduction of mycotoxin contamination in plants. Pydiflumetofen is also useful in increasing yield, in particular in cereals eg. wheat.

## Claims

### Claim 1

A method of reducing deoxynivalenol contamination in a plant consisting of applying to the plant as a foliar application an effective amount of a compound according to formula (I):
having the IUPAC name 3-(Difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)-2-propanyl]-1H-pyrazole-4-carboxamide; or a tautomer or isomer or enantiomer thereof, and a Group 1 triazole compound selected from the group consisting of cyproconazole, difenconazole, tebuconazole, metconazole, epoxiconazole, tetraconazole, and propiconazole.

### Claim 2 (depends on 1)

The method according to claim 1 wherein the compound of Formula I and the Group 1 triazole are applied in a liquid composition.

### Claim 3 (depends on 1)

A plant which has been treated by the method according to claim 1.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the plant is wheat.

### Claim 5 (depends on 1)

The method according to claim 1, wherein the plant has at least 80% less deoxynivalenol contamination than a plant which has not been treated.

### Claim 6 (depends on 1)

The method of claim 1, wherein the compound of formula (I) and the Group 1 triazole compound are applied during flowering.

### Claim 7

A method for increasing plant yield by reducing deoxynivalenol contamination in a plant, comprising applying to the plant as a foliar application an effective amount of a compound according to formula (I):
having the IUPAC name 3-(Difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)-2-propanyl]-1H-pyrazole-4-carboxamide; or a tautomer or isomer or enantiomer thereof, and a Group 1 triazole compound selected from the group consisting of cyproconazole, difenconazole, tebuconazole, metconazole, epoxiconazole, tetraconazole, and propiconazole.

### Claim 8 (depends on 7)

The method according to claim 7 wherein the compound of formula (I) and the Group 1 triazole compound are applied in a liquid composition.