# US 10,864,317 B2 · Time controlled periodic infusion

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- Number: US 10,864,317 B2
- Document ID: US10864317B2
- Status: Granted
- Kind: B2
- Application number: 15/517,674
- Filed: 2015-10-28
- Published: 2018-10-18
- Granted: 2020-12-15
- Earliest claimed: 2014-10-28
- Assignees: Ferrosan Medical Devices A/S
- Applicants: Ferrosan Medical Devices A/S
- Inventors: Kai Lange; Christian Rothe; Frederik Sonnenborg; Arnt Larsen Lund; Søren Falkesgaard Ørts; Claus Reuber
- Web page: https://patentgrep.com/patent/US10864317B2

## CPC

- A61M 5/1424: {Manually operated pumps}
- A61K 9/0019: {Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00)}
- A61K 31/167: having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A61K 31/445: Non condensed piperidines, e.g. piperocaine
- A61M 5/14248: {of the skin patch type}
- A61M 5/1452: {pressurised by means of pistons}
- A61M 5/16854: {by monitoring line pressure}
- A61M 5/14244: {adapted to be carried by the patient, e.g. portable on the body}
- A61M 2005/14208: {with a programmable infusion control system, characterised by the infusion program}
- A61M 2202/048: Anaesthetics
- A61M 2205/3334: Measuring or controlling the flow rate
- A61M 2205/3584: using modem, internet or Bluetooth®
- A61M 2205/52: with memories providing a history of measured variating parameters of apparatus or patient
- A61M 2205/8206: battery-operated
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

The present disclosure relates to administration of fluid medication, in particular medication and dosing regimen for management of pain, more specifically to an anesthetic and dosing regimen for anesthetic for perioperative pain management and/or for palliative care. The present disclosure relates further to a medication pump and a method for delivering medication using the medication pump.

## Claims

### Claim 1

A wearable administration system configured for delivering a time-controlled periodic infusion of medication to a target, comprising:
a medication pump;
a control unit configured to automatically operate said medication pump to periodically infuse said medication utilizing flow rates between 30 mL/h and 1200 mL/h to define a preset infusion sequence with an infusion volume of between 1-20 mL during an infusion time of between 1-20 minutes with a period of 1-48 hours.

### Claim 2 (depends on 1)

The administration system according to claim 1, wherein said control unit comprises manual operation means, configured such that when manually operated, said control unit is configured to operate said medication pump to infuse said medication utilizing flow rates between 30 mL/h and 1200 mL/h to define a preset infusion sequence with an infusion volume of between 1-20 mL during an infusion time of between 1-20 minutes with a period of 1-48 hours.

### Claim 3 (depends on 1)

The administration system according to claim 1, wherein the control unit is further configured to automatically operate said medication pump to periodically infuse a plurality of infusion sequences such that each of said infusion sequences are separated by a preset dwell-time that is different from the period.

### Claim 4 (depends on 3)

The administration system according to claim 3, wherein the control unit is configured to alter the preset dwell-time if being operated manually.

### Claim 5 (depends on 1)

The administration system according to claim 1, wherein said control unit comprises manual setup means, configured such that said infusion volume, and/or infusion time and/or period is/are set up manually.

### Claim 6 (depends on 5)

The administration system according to claim 5, wherein said manual setup means is configured to be set up such that said infusion volume, and/or infusion time and/or period is/are locked.

### Claim 7 (depends on 1)

The administration system according to claim 1, wherein said control unit is driven by one or more batteries and/or a portable power source.

### Claim 8 (depends on 1)

The administration system according to claim 1, wherein said medication pump and said control unit are integrated in one component.

### Claim 9 (depends on 8)

The administration system according to claim 8, wherein said component is disposable.

### Claim 10 (depends on 8)

The administration system according to claim 8, wherein said component is a single-use system.

### Claim 11 (depends on 1)

The administration system according to claim 1 further comprising fastening means configured for fastening the administration system to a body or to clothes on the body.

### Claim 12 (depends on 1)

The administration system according claim 1, wherein said medication pump and said control unit are removably integrated in one unit.

### Claim 13 (depends on 12)

A delivery system for delivering a time-controlled periodic infusion of medication to a target, comprising:
a wearable administration system according to claim 12; and
a catheter.

### Claim 14 (depends on 13)

The delivery system according to claim 13, wherein said catheter is a peripheral indwelling catheter or an epidural catheter.

### Claim 15

A method for delivering a time-controlled periodic infusion of medication to a target from a wearable administration system comprising a medication pump and a control unit, comprising:
a) infusing said medication utilizing flow rates between 30 mL/h and 1200 mL/h to define a preset infusion sequence with an infusion volume of between 1-20 mL during an infusion time of between 1-20 minutes by automatically operating said pump via said control unit;
b) waiting a period of 1-48 hours; and
c) repeating a-b.

### Claim 16 (depends on 15)

The method according to claim 15, further comprising optionally, not to be repeated by said administration system, infusing said medication utilizing flow rates between 30 mL/h and 1200 mL/h to define a preset infusion sequence with an infusion volume of between 1-20 mL during an infusion time of between 1-20 minutes by manually operating said pump via said control unit.

### Claim 17 (depends on 15)

The method according to claim 15, wherein said infusion volume and/or said infusion time and/or said period are computer implemented into said administration system.

### Claim 18 (depends on 15)

The method according to claim 15, wherein said infusion volume and/or said infusion time and/or said period are pre-defined in said administration system.

### Claim 19 (depends on 15)

The method according to claim 15, wherein said infusion volume and/or said infusion time and/or said period are user-defined in said administration system.
