# US 10,864,239 B1 · High yield extraction method for and products of kanna plants > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,864,239 B1 - Document ID: US10864239B1 - Status: Granted - Kind: B1 - Application number: 16/668,474 - Filed: 2019-10-30 - Granted: 2020-12-15 - Earliest claimed: 2019-10-30 - Assignees: Plant Synergy Inc. - Applicants: Plant Synergy Inc. - Inventors: Armand Bytton - Web page: https://patentgrep.com/patent/US10864239B1 ## CPC - A61K 36/185: Magnoliopsida (dicotyledons) - A61K 31/404: Indoles, e.g. pindolol - A61K 31/658: {o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol} - A61K 2236/333: using mixed solvents, e.g. 70% EtOH - A61K 2236/39: Complex extraction schemes, e.g. fractionation or repeated extraction steps - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) ## Abstract A method of extracting a Kanna plant comprising the steps of harvesting and drying the plant; extracting the alkaloids from the plant in a solvent; filtering the solvent-Kanna plant mixture to remove the solvent and extracted alkaloids from a spent plant matter; drying the spent plant matter; purifying and separating the extracted alkaloids from the solvent; and mixing the purified alkaloids back into the dried spent plant matter. Also, products of the method include vaporizing liquids, medicinal compositions, kief compositions, rolling papers, and filters for tobacco and vaporizing equipment comprising the mixture of the purified alkaloids and the dried spent plant matter produced according to the method. Further, a Kanna plant having a total alkaloid content of 3.5-18%, of which 40% of the total alkaloid content is 0.5-40% mesembrine at a ratio of 2:5 for mesembrine:total alkaloid content. ## Claims ### Claim 1 A method of extracting a Kanna plant comprising the steps of: harvesting and drying the Kanna plant; extracting alkaloids comprising Mesembrine from the Kanna plant in a solvent; filtering the solvent-Kanna plant mixture to remove the solvent and extracted alkaloids from a spent Kanna plant matter; drying the spent Kanna plant matter; purifying and separating the extracted alkaloids from the solvent; and mixing the extracted alkaloids back into the dried spent Kanna plant matter. ### Claim 2 (depends on 1) The method according to claim 1, wherein the Kanna plant has a total alkaloid content of 3.5-18%, and wherein the total alkaloid content comprises 0.5-40% Mesembrine. ### Claim 3 (depends on 1) The method according to claim 1, wherein the solvent is selected from the group consisting of ethanol, methanol, hydroalcohol, acetone, acetonitrile, hexane, heptane, hexane, chloroform, dichloromethane, water, and mixtures thereof. ### Claim 4 (depends on 3) The method according to claim 3, wherein the solvent is ethanol. ### Claim 5 (depends on 1) The method according to claim 1, wherein the removal of the solvent is by a process selected from the group consisting of distillation, open-dish evaporation, reduced-pressure evaporation, rotary evaporation, vacuum, lyophilization, or a combination of methods thereof. ### Claim 6 (depends on 5) The method according to claim 5, wherein the removal of the solvent is by rotary evaporation. ### Claim 7 (depends on 1) The method according to claim 1, wherein the purification and separation of the alkaloids is carried out by passing the solvent and extracted alkaloids over or through a process selected from the group consisting of column chromatography comprising a reverse stationary phase, a normal stationary phase or combination thereof, ion-exchange chromatography, gel-permeation (molecular sieve) chromatography, affinity chromatography, paper chromatography, thin-layer chromatography, gas chromatography, dye-ligand chromatography, hydrophobic interaction chromatography, pseudoaffinity chromatography, and high-pressure liquid chromatography (HPLC). ### Claim 8 (depends on 1) The method according to claim 1, wherein the method further comprises adding cannabidiols (CBD) to the Kanna plant and the solvent during extraction. ### Claim 9 (depends on 8) The method according to claim 8, wherein the cannabidiols source is selected from the group consisting of hemp plant, crude hemp oil, kief, nabiximol, epidiolex, and combinations thereof. ### Claim 10 (depends on 9) The method according to claim 9, wherein the cannabidiols source is crude hemp oil. ### Claim 11 (depends on 1) The method according to claim 1, wherein the method further comprises adding cannabidiols (CBD) to the mixture of the purified alkaloids and the dried spent Kanna plant matter. ### Claim 12 (depends on 11) The method according to claim 11, wherein the cannabidiols source is selected from the group consisting of hemp plant, crude hemp oil, kief, nabiximol, epidiolex, and combinations thereof. ### Claim 13 (depends on 12) The method according to claim 12, wherein the cannabidiol source is crude hemp oil. ### Claim 14 (depends on 1) The method according to claim 1, wherein the method further comprises solubilizing the mixture of the purified alkaloids and the dried spent Kanna plant matter in a second solvent. ### Claim 15 (depends on 14) The method according to claim 14, wherein the second solvent is selected from the group consisting of ethanol, methanol, hydroalcohol, acetone, acetonitrile, hexane, heptane, hexane, chloroform, dichloromethane, water, and mixtures thereof.