# US 10,864,223 B2 · Lipid compositions

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- Number: US 10,864,223 B2
- Document ID: US10864223B2
- Status: Granted
- Kind: B2
- Application number: 15/040,347
- Filed: 2016-02-10
- Published: 2016-08-11
- Granted: 2020-12-15
- Earliest claimed: 2015-02-11
- Assignees: Aker Biomarine Antarctic AS
- Applicants: Aker BioMarine Antarctic AS
- Inventors: Finn Myhren; Nils Hoem; Asgeir Saebo; Anil R. Oroskar; Asha A. Oroskar; Anantha Krishna Mallia
- Web page: https://patentgrep.com/patent/US10864223B2

## CPC

- A61K 31/685: one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A23K 20/158: Fatty acids; Fats; Products containing oils or fats
- A23K 20/179: Colouring agents, e.g. pigmenting or dyeing agents
- A23K 20/26: Compounds containing phosphorus
- A23L 33/12: Fatty acids or derivatives thereof
- A61K 9/0053: {Mouth and digestive tract, i.e. intraoral and peroral administration}
- A61K 31/20: having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K 31/215: of carboxylic acids
- A61K 31/23: of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K 31/683: Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K 35/612: Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
- C11B 3/006: {by extraction}
- C11B 3/16: by mechanical means
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23K: FODDER
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- C11B: PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES (drying-oils C09F)

## Abstract

The present invention provides improved processes for extracting and preparing lipids from biological sources for use in pharmaceuticals, nutraceuticals and functional foods.

## Claims

### Claim 1

A desalted krill lipid composition comprising:
from about 30% to 50% w/w phospholipids;
from about 32% to 52% w/w triglycerides;
and wherein the composition has the following properties:
a) the composition comprises less than about 0.2% w/w inorganic salts;
b) the composition comprises less than about 2 ppm Cu++; and
c) the composition comprises less than about 3 ppm total arsenic.

### Claim 2 (depends on 1)

The composition of claim 1, said composition further characterized in comprising from about 3% w/w to 13% w/w free fatty acids.

### Claim 3 (depends on 1)

The composition of claim 1, said composition further characterized in comprising from about 0.5% w/w to 5% w/w lysophospholipids.

### Claim 4 (depends on 1)

The composition of claim 1, said composition further characterized in comprising less than about 2 mg N/100 g.

### Claim 5 (depends on 1)

The composition of claim 1, said composition further characterized in comprising from about 0.01% to about 1% w/w ethyl esters.

### Claim 6 (depends on 1)

The composition of claim 1, said composition further characterized in having a conductivity of less than about 20 μS/cm when measured with 5% dry matter in 95% ethanol.

### Claim 7 (depends on 1)

The composition of claim 1, said composition further characterized in having a viscosity of from about 100 to 400 mPas at 25° C.

### Claim 8 (depends on 1)

The composition of claim 1, said composition further characterized in comprising from about 20 ppm to about 2000 ppm astaxanthin esters.

### Claim 9

A krill phospholipid concentrate comprising:
from about 50% to 85% w/w phospholipids;
from about 5% to 35% w/w triglycerides;
and wherein the composition has the following properties:
(a) the composition comprises less than about 0.2% w/w inorganic salts; and
(b) the composition has a viscosity of from about 600 to 1600 mPas at 35° C.

### Claim 10 (depends on 9)

The composition of claim 9, said composition further characterized in comprising from about 2% w/w to 13% w/w free fatty acids, from about 0.5% w/w to 10% w/w lysophospholipids, less than about 2 mg N/100 g, less than about 2 ppm Cu++; less than about 3 ppm total arsenic; from about 0.01% to about 1% w/w ethyl esters; less than about 100 ppm astaxanthin esters and having a conductivity of less than about 20 μS/cm when measured with 5% dry matter in 95% ethanol.

### Claim 11 (depends on 9)

The composition of claim 9, said composition further characterized in having a conductivity of less than about 20 μS/cm when measured with 5% dry matter in 95% ethanol.

### Claim 12 (depends on 11)

The composition of claim 11, said composition further characterized in comprising less than about 2 ppm Cu++ and less than about 3 ppm total arsenic.

### Claim 13 (depends on 12)

The composition of claim 12, said composition further characterized in comprising less than about 2 mg N/100 g.

### Claim 14 (depends on 9)

The composition of claim 9, said composition further characterized in comprising less than about 2 mg N/100 g, less than about 2 ppm Cu++, less than about 3 ppm total arsenic, and in having a conductivity of less than about 20 μS/cm when measured with 5% dry matter in 95% ethanol.