# US 10,863,912 B2 · System and method for analyzing electroencephalogram signals

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- Number: US 10,863,912 B2
- Document ID: US10863912B2
- Status: Granted
- Kind: B2
- Application number: 15/685,985
- Filed: 2017-08-24
- Published: 2019-02-28
- Granted: 2020-12-15
- Earliest claimed: 2017-08-24
- Assignees: Myneurva Holdings, Inc.
- Applicants: Myneurva Holdings, Inc.
- Inventors: Frederick Scott Starr; Sean O'Connor
- Web page: https://patentgrep.com/patent/US10863912B2

## CPC

- A61B 5/374: Detecting the frequency distribution of signals, e.g. detecting delta, theta, alpha, beta or gamma waves
- A61B 5/7275: {Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor}
- G16H 40/63: for local operation
- G16H 50/70: for mining of medical data, e.g. analysing previous cases of other patients
- A61B 5/16: Devices for psychotechnics (using teaching or educational appliances G09B1/00 - G09B7/00); Testing reaction times {; Devices for evaluating the psychological state}
- A61B 5/6814: {Head}
- A61B 5/7257: {using Fourier transforms}
- A61B 5/726: {using Wavelet transforms}
- A61B 2562/046: in a matrix array
- G06F 16/22: Indexing; Data structures therefor; Storage structures
- G16H 10/60: for patient-specific data, e.g. for electronic patient records
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N)

## Abstract

A system, a computer readable storage medium, and a method for analyzing electroencephalogram signals can include a plurality of sensors configured to contact a skull and capture the electroencephalogram signals, one or more computer memory units for storing computer instructions and data, and one or more processors configured to perform the operations of clustering the electroencephalogram signals using at least stored objective data and added subjective data including patient profile data to provide clustered data results and predicting one or more among a medical diagnosis, assessment, plan, necessary forms, or recommendations for follow up based on the clustered data results.

## Claims

### Claim 1

A system for analyzing electroencephalogram signals, comprising:
a plurality of sensors configured to contact a skull of a patient and capture electroencephalogram signals of the patient;
one or more computer memory units for storing computer instructions and data; and
one or more processors operatively coupled to the one or more computer memory units and the plurality of sensors, the one or more processors configured to perform the operations of:
clustering the electroencephalogram signals using at least stored objective data and added subjective data including patient profile data to provide clustered data results; and
predicting the patient's medical diagnosis, including an assessment, or recommendations for follow up, based on the clustered data results;
wherein the one or more processors present options for predicting the diagnosis using a selection among an unguided prediction, a guided prediction, a narrowed down prediction, or a flat prediction.

### Claim 2 (depends on 1)

The system of claim 1, wherein the one or more processors are configured to perform data transformation of the electroencephalogram signals to enable a comparison of normalized electroencephalogram signals with the stored objective and the added subjective data.

### Claim 3 (depends on 2)

The system of claim 2, wherein the data transformation is done by using one or more of the analysis methods comprising absolute power analysis, relative power analysis, amplitude asymmetry connectivity analysis, coherence connectivity analysis, phase lag analysis, phase shift analysis, phase lock analysis, current source density analysis, evoked potential analysis, or low resolution electrographic analysis.

### Claim 4 (depends on 2)

The system of claim 2, wherein the data transformation is done by using absolute power analysis by performing a Fast Fourier Transform between the electroencephalogram signals and a complex Morlet wavelet sine wave for a frequency range of the electroencephalogram signals captured and comparing the Fast Fourier Transform to a derived normal based on a Z-score Gaussian distribution.

### Claim 5 (depends on 1)

The system of claim 1, wherein one or more blocks in a blockchain in the one or more memory units includes a private encryption key.

### Claim 6 (depends on 1)

The system of claim 1, wherein the one or more processors clusters the electroencephalogram signals over different frequent bands and further clusters the electroencephalogram signals with cloud based stored patterns in a database for analysis and prediction.

### Claim 7 (depends on 1)

The system of claim 1, wherein the one or more processors provide a display on an input interface enabling an expert to correct or verify the diagnosis predicted by the system.

### Claim 8 (depends on 1)

The system of claim 1, wherein the one or more processors are configured to allow an expert to correct and/or verify the predicted diagnosis based on the patient's symptoms, and electroencephalogram signals stored in a database.

### Claim 9 (depends on 1)

The system of claim 1, wherein the plurality of sensors are electroencephalogram sensors having prongs extending less than two centimeters from a central hub at equidistant angles from one another and forming podia extending outwards at an angle from a shaft and further formed of graphene and wherein each sensor has a prong extending from the base of the podia and contains individual faraday cages on each podia.
