# US 10,863,903 B2 · Ocular system and method > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,863,903 B2 - Document ID: US10863903B2 - Status: Granted - Kind: B2 - Application number: 16/010,486 - Filed: 2018-06-17 - Published: 2019-12-19 - Granted: 2020-12-15 - Earliest claimed: 2018-06-17 - Assignees: Advanced Ophthalmics LLC - Applicants: John Naber; Doug Jackson; Rich Eiferman - Inventors: John Naber; Doug Jackson; Rich Eiferman - Web page: https://patentgrep.com/patent/US10863903B2 ## CPC - A61B 3/16: for measuring intraocular pressure, e.g. tonometers - A61B 3/0025: {characterised by electronic signal processing, e.g. eye models} - A61F 9/00781: {Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002)} - H05K 1/0393: {Flexible materials (H05K1/038 takes precedence; specific organic compositions are classified in H05K1/0313 and subgroups)} - A61B 2562/12: Manufacturing methods specially adapted for producing sensors for in-vivo measurements - H05K 1/189: characterised by the use of flexible or folded printed circuits - H05K 2201/056: Folded around rigid support or component - H05K 2201/0999: Circuit printed on or in housing, e.g. housing as PCB; Circuit printed on the case of a component; PCB affixed to housing - H05K 2201/10015: Non-printed capacitor - H05K 2201/10151: Sensor - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - H05K: PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS ## Abstract A system and method for remotely monitoring Inter Ocular Pressure (IOP) is disclosed. The system and method verify proper operation of glaucoma drainage, measure and potentially affect Intra-Ocular Pressure (IOP), and facilitate remote disease management of e.g. glaucoma, among other ocular diseases. ## Claims ### Claim 1 A method of manufacturing a glaucoma inter ocular pressure (IOP) system, comprising: configuring the system to have a shell comprising eyelets, a reservoir, and a drain tube; integrating an arrangement of low-power electronics, at least one electronic sensors, and wireless telemetry to form a drainage device within the shell; configuring the arrangement of low-power electronics to convert at least one outputs from the at least one sensors into a signal; facilitating the arrangement such that the signal is wirelessly conveyed to a separate reader through the wireless telemetry; and locating the reader in close proximity to the drainage device during eventual use. ### Claim 2 (depends on 1) The method of claim 1, further comprising: configuring the shell to have a plurality of contours that conform with typical contours of a human eye. ### Claim 3 (depends on 2) The method of claim 2, further comprising: embedding the at least one electronic sensors, wireless telemetry, and arrangement of low-power electronics within a flexible printed circuit board. ### Claim 4 (depends on 3) The method of claim 3, further comprising: architecting the flexible printed circuit board to exactly conform with a plurality of contours within the shell. ### Claim 5 (depends on 3) The method of claim 3, further comprising: the flexible printed circuit board adhering to greater than 80% of a surface area of the shell. ### Claim 6 (depends on 3) The method of claim 3, further comprising: the flexible printed circuit board having system eyelets which match with and adhere to the eyelets of the shell. ### Claim 7 (depends on 3) The method of claim 3, further comprising: the reader providing power to the flexible printed circuit board. ### Claim 8 (depends on 3) The method of claim 3, further comprising: a super capacitor providing power to the flexible printed circuit board. ### Claim 9 (depends on 3) The method of claim 3, further comprising: forming the flexible printed circuit board to also be stretchable, thereby aiding in shaping a substrate over at least one contours of the shell; and incorporating alternative patterns of conductors to assist in shaping the substrate without breaking the conductors. ### Claim 10 (depends on 3) The method of claim 3, further comprising: forming a domed cap over the flexible printed circuit board, thereby preventing corners of the circuit board from damaging a coating and to create a smooth shape for eye-tissue to rest against; locating a buffer layer of silicone polymer (PDMS) or polymethyl acrylate (PMMA) to adjoin against a sclera, thereby reducing forming of hard and soft eye-tissue areas due to potential contact with components within the flexible printed circuit board. ### Claim 11 (depends on 1) The method of claim 1, further comprising: molding the shell using low-temperature under 120° C. polyvinyl methyl siloxane (PVMS) which cures at room-temperature. ### Claim 12 (depends on 1) The method of claim 1, further comprising: manufacturing the shell using two-step process, comprising; molding a first portion of the shell; molding a second portion of the shell; gluing the two portions together; and dipping the two portions into a coating. ### Claim 13 (depends on 1) The method of claim 1, further comprising: implementing the system described herein using a single conductive substrate. ### Claim 14 (depends on 1) The method of claim 1, further comprising: implementing a first substrate holding the various electronics components; and afterwards, after testing and verification, adding a separate substrate. ### Claim 15 (depends on 1) The method of claim 1, further comprising: embedding the at least one electronic sensors, wireless telemetry, arrangement of low-power electronics, and flexible printed circuit board within a pre-existing pre-purchased pre-tested glaucoma IOP system. ### Claim 16 (depends on 1) The method of claim 1, further comprising: forming the shell, then writing conductive traces onto the shell; then inkjet printing a plurality of conductors onto the shell; and coating over the top of the plurality of conductors.