Infusion systems and methods for prospective closed-loop adjustments

A method of operating an infusion device capable of delivering insulin to a patient, the method comprising:

• determining, by a control system associated with the infusion device, a probable meal at a future time of day based at least in part on historical meal data associated with the patient and a current time of day;
• automatically adjusting, by the control system, a closed-loop control parameter at the current time of day in advance of the future time of day in a manner that is influenced by the probable meal;
• and
• automatically operating, by the control system, an actuation arrangement of the infusion device to deliver the insulin to the patient based at least in part on a current sensor glucose measurement for the patient and the adjusted closed-loop control parameter.

An infusion system comprising:

• an actuation arrangement operable to deliver fluid to a patient, the fluid influencing a physiological condition of the patient;
• a sensing arrangement to provide a current measurement value indicative of the physiological condition of the patient;
• a data storage element to maintain historical meal data for the patient;
• and
• a control system coupled to the actuation arrangement, the sensing arrangement, and the data storage element to predict a future meal based at least in part on the historical meal data and a current time of day, automatically adjust a closed-loop control parameter in advance of the future meal in a manner that is influenced by the future meal, and automatically operate the actuation arrangement to deliver the fluid to the patient based at least in part on the current measurement value and the adjusted closed-loop control parameter.