System and method for the detection of gamma radiation from a radioactive analyte

A method for the ex vivo real-time detection over a period of time of gamma radiation emitted by a subject from the administration of a radioactive analyte that decays in vivo, the method comprising:

• (i) applying at least one ex vivo gamma radiation measurement sensor proximate to a point of administration on the subject of the radioactive analyte;
• (ii) detecting gamma radiation over a desired period of time and producing signal data associated with the desired period of time;
• (iii) amplifying the signal data using a signal amplifier in operable communication with the gamma radiation sensor, wherein the measurement sensor having at least one sensor output for such amplified signal data and outputting the amplified signal data;
• (iv) processing the amplified signal data using a computer processor in operative communication with a non-transient memory and the measurement sensor output by performing the steps of:
• (a) receiving the amplified signal data associated with the desired period of time;
• (b) from the non-transient memory, accessing reference data distributed over a reference period of time;
• and
• (c) determining if the administration of the radioactive analyte properly administered the radioactive analyte into the subject by comparing the amplified signal data to the reference data using a parametric model.

A system for the ex vivo-real-time detection of gamma radiation emitted by a subject from the administration of radioactive analyte that decays in vivo, the system comprising:

• at least one ex vivo gamma radiation measurement sensor to detect gamma radiation and produce signal data associated with the detection of gamma radiation, the ex vivo measurement sensor adapted to sensing gamma radiation proximate a region of interest on the subject of the radioactive analyte;
• a signal amplifier in operable communication with the gamma radiation sensor, the signal amplifier adapted to amplify the signal data, the measurement sensor having at least one sensor output for such amplified signal data;
• at least one computer processor and a non-transient memory, the computer processor in operable communication with the non-transient memory and the measurement sensor output;
• wherein the non-transient memory includes computer program code executable by the at least one computer processor, the computer program code configured for performing the steps of receiving the amplified signal data, accessing reference data, and comparing the amplified signal data to the reference data using a predictive model to determine the probability of sufficient administration of the radioactive analyte to the subject.