US 10,852,378 B2 · Method for optimizing the predetermination of the time profile of a contrast agent concentration in diagnostic imaging using a magnetic resonance system

Abstract

A method of predetermining the time profile of a contrast agent concentration at a vessel position is provided in the context of contrast agent-enhanced MRI of a region of interest only during the initial flooding-in phase of the contrast agent into the vessel situated in the region of interest. The method includes establishing a broadening of a contrast agent bolus profile according to the equation ΔW=W2−W1 wherein W1 is a first width of the contrast agent bolus profile at a first vessel position and W2 is a second width of a contrast agent concentration profile at a second vessel position within the region of interest. The broadening is established by determining at least one flow parameter which is dependent on at least one blood flow property of the patient at a third vessel position thereof and which correlates with the broadening of the contrast agent profile.

Claims24

Dependent claims

A method of predetermining a time profile of contrast agent concentration at a position in a blood vessel of a patient in the context of contrast agent-enhanced magnetic resonance (MR) imaging of a region of interest only during an initial flooding-in phase of the contrast agent into the blood vessel situated in the region of interest, the method comprising:

establishing an expected broadening of a contrast agent bolus profile B(t) according to the equation ΔW=W2−W1 wherein W1 is a first width of the contrast agent bolus profile B(t) at a predetermined first vessel position of the patient and W2 is a second width of a contrast agent concentration profile K(t) at a predetermined second vessel position situated in the region of interest of the patient;
such that the expected broadening is established by determining at least one flow parameter which is dependent on at least one blood flow property of the patient at a third vessel position thereof and which correlates with the expected broadening of the contrast agent bolus profile B(t).

A method of predetermining a time profile of contrast agent concentration at a position in a blood vessel in a region of interest of a patient (P) in connection with a contrast agent-enhanced magnetic resonance (MR) imaging procedure to be performed on the patient, the method comprising:

establishing a correlation between a broadening (ΔW=W2−W1) of at least one contrast agent bolus profile (B(t)) having a first width (W1) at a first vessel position (P1) in relation to a contrast agent concentration profile (K(t)) having a second width (W2) at a second vessel position (P2), the correlation being established using a flow parameter (PG) dependent upon at least a blood flow property (fB) of the patient (P) at a third vessel position (P3) thereof and taking into account at least one patient parameter (PP) of an examined patient collective;
determining from the patient (P) at least one flow parameter (Ppa) currently representative thereof;
selecting a desired contrast agent concentration profile (K(t)) to be achieved at the second vessel position (P2) and, using the correlation, determining a necessary contrast agent bolus profile (B(t)) required therefor, taking into account at least one patient parameter (PP) of the patient (P);
and
enabling the necessary contrast agent bolus profile (B(t)) to be one of selectable from or transmittable to an injection device for use in a contrast agent-enhanced MR examination.

2 more elements

Dependencies are inferred from the claim text.

Method for optimizing the predetermination of the time profile of a contrast agent concentration in diagnostic imaging using a magnetic resonance system

Life of this patent

Method for optimizing the predetermination of the time profile of a contrast agent concentration in diagnostic imaging using a magnetic resonance system

Life of this patent

Abstract

Claims24