Optical assay device with pneumatic sample actuation
AssigneeAbbott Point of Care Inc.
InventorsPierre Emeric, Graham Davis, Thomas Ewart, Sergey Gershtein
Life of this patent
Estimating the term…
Abstract
This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to test devices, e.g., cartridges, methods and systems, wherein the test devices have an entry port configured to receive a test sample into a holding chamber; a first conduit having at least one lateral flow test strip; and a displacement device, such as a pneumatic pump, configured to move a portion of said test sample from said holding chamber into said first conduit. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.
Claims20
An analyte test cartridge comprising:
- a sample entry port to receive a test sample;
- a sample holding chamber connected to the sample entry port;
- a conduit fluidically connected to the sample holding chamber, the conduit comprising
- a labeling zone comprising a labeled antibody specific for an analyte and comprising a label,
- and a capture zone located downstream from the labeling zone and comprising a porous plug with a capture antibody for the analyte;
- and
- a displacement device capable of mixing the test sample with the labeled antibody and to move the test sample through at least a portion of the analyte test cartridge from the labeling zone to the capture zone.
An analyte test cartridge comprising:
- a sample entry port to receive a test sample;
- a sample holding chamber connected to the sample entry port;
- a conduit fluidically connected to the sample holding chamber, the conduit comprising
- a labelling zone comprising a plurality of labeled antibodies specific for a plurality of analytes,
- and one or more capture zones, the one or more capture zones comprising a
- plurality of capture antibodies for the plurality of analytes;
- and
- a displacement device capable of mixing the test sample with the plurality of the labeled antibodies and to move the test sample through at least a portion of the analyte test cartridge from the labeling zone to the one or more capture zones.
Dependencies are inferred from the claim text.