Fluidic device and methods of use for processing tissue for pathology

A fluidic device comprising:

• one or more curved channels each having a channel input and a channel output, wherein the one or more curved channels each have a substantially circular cross-section, wherein the one or more curved channels include at least a first segment between the channel input and the channel output, a second segment between the first segment and the channel output, and a third segment between the second segment and the channel output, and wherein the first segment has a first diameter that is different than a second diameter of the second segment, and wherein the third segment has a third diameter that is different than the second diameter;
• an input interface directly coupling the channel input of the one or more curved channels to an exterior of the fluidic device, wherein the input interface is configured to receive a biological tissue sample having a diameter that is about 10% to about 20% less than the diameter of the one or more curved channels, and wherein the input interface comprises a septum that provides a fluid-tight seal between the exterior of the fluidic device and the one or more curved channels;
• and
• an output interface directly coupling the channel output of the one or more curved channels to the exterior of the fluidic device, wherein an entire length of each of the one or more curved channels from the input interface to the output interface has a diameter greater than 0.2 mm and up to 5 mm.