Ready to use porcine vaccine
AssigneeIntervet Inc.
InventorsMichelle Allen, Mark Garrett, Urs Peter Bruderer, Martinus Antonius Johannes Thijssen
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Abstract
The invention relates to certain methods for the determination of an antigen content of a first antigen in a mixture comprising two or more antigens. The invention also relates to a potency test for an antigen in a combination vaccine. The method allows the determination of the antigen content in a mixture additionally comprising antibodies that are capable of binding with the antigen.
Claims16
A ready to use vaccine comprising a porcine circovirus type 2 (PCV-2) antigen and a Mycoplasma hyopneumoniae (M. hyo) antigen;
- wherein the M. hyo antigen originates from media comprising serum that also contains an antibody that is capable of binding to the PCV-2 antigen;
- wherein the M. hyo antigen has been separated from said antibody;
- and wherein said composition is obtained by the method of:
- A. separating the M. hyo antigen from said antibody by either centrifugation or an immuno-depletion step;
- wherein the M. hyo antigen is separated from said antibody;
- and
- B. mixing the PCV-2 antigen with the M. hyo antigen separated from said antibody.
A ready to use vaccine comprising a porcine circovirus type 2 (PCV-2) antigen and a Mycoplasma hyopneumoniae (M. hyo) antigen;
- wherein the M. hyo antigen originates from media comprising serum that also contains an antibody that is capable of binding to the PCV-2 antigen;
- and wherein the M. hyo antigen had been separated from said antibody prior to mixing the M. hyo antigen with the PCV-2 antigen to form said ready to use vaccine.
Dependencies are inferred from the claim text.