Systems and methods for analyte sensing in physiological gas samples
AssigneeBoston Scientific Scimed, Inc.
InventorsDavid W. Kelly, Gregory J. Sherwood, Justin Theodore Nelson
Life of this patent
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Abstract
Embodiments herein relate to systems and devices for measuring analyte presence on graphene varactors, which can be used for analyte sensing in physiological gas samples. In an embodiment, a system for measuring analyte presence on a graphene varactor is included having a capacitance to digital converter (CDC) and a graphene varactor. The CDC can be in electrical communication with the graphene varactor and can be configured to measure the capacitance of the graphene varactor in response to an excitation signal over a plurality of DC bias voltages. Other embodiments are also included herein.
Claims17
A system for measuring analyte presence on a graphene varactor comprising:
- a capacitance to digital converter (CDC);
- a graphene varactor;
- the CDC in electrical communication with the graphene varactor and configured to measure the capacitance of the graphene varactor in response to an excitation signal over a plurality of DC bias voltages;
- two programmable digital to analog converters (DACs);
- and
- a switch, the CDC in electrical communication with the switch and controlling the switch to selectively provide communication with output voltages of the two programmable digital to analog converters (DACs);
- wherein the programmed voltage difference between the DACs determines the excitation amplitude, and the difference between the programmed average voltage of the DACs and the bias at the CDC input determines the DC bias voltage.
A method for measuring analyte presence on a graphene varactor comprising:
- controlling a switch to selectively provide communication with output voltages of two programmable digital to analog converters (DACs), the programmed voltage difference between the DACs determining an excitation amplitude, and the difference between the programmed average voltage of the DACs and the bias at the CDC input determining a DC bias voltage;
- measuring a capacitance of the graphene varactor over a range of DC bias voltages;
- comparing the measured capacitance at one or more DC bias voltages to one or more corresponding baseline capacitance values;
- and
- determining the presence or absence of an analyte based on the comparison.
Dependencies are inferred from the claim text.