Immunostimulatory plasmids
AssigneeBayer Animal Health GmbH
InventorsMarc Munnes, Christian Weiss, Elisabeth Feldhues, Romina G. Schauer, Albert Abraham, Andrea Eicker, Hermann Wehlmann
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Abstract
The present invention relates to immunomodulator compositions and methods of use as well as methods of making. The immunomodulator compositions comprise immunostimulatory plasmids, or DNA sequence, capable of eliciting an immune response in a recipient subject. Further, the immunostimulatory plasmids, or DNA sequence, do not contain antibiotic resistance coding sequence to help reduce the potential of horizontal transfer of antibiotic resistance in a population.
Claims20
A method of stimulating an immune response in a subject comprising administering to the subject an immunostimulatory composition comprising:
- a. a nucleic acid molecule having at least 84% sequence homology with the sequence of SEQ ID NO:
- 4 and at least 200 CpG dinucleotides;
- and
- b. a cationic liposome delivery vehicle,
- wherein an immune response is stimulated in the subject.
Dependencies are inferred from the claim text.