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US 10,851,333 B2Granted
Biomanufacturing system, method, and 3D bioprinting hardware in a reduced gravity environment
AssigneeTechshot, Inc.
InventorsJohn C. Vellinger, Eugene Boland, Michael A. Kurk, Krystal Milliner, Nester Samuel Logan
Life of this patent
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Abstract
A method, apparatus, and system are provided for the printing and maturation of living tissue in an Earth-referenced reduced gravity environment such as that found on a spacecraft or on other celestial bodies. The printing may be three-dimensional structures. The printed structures may be manufactured from low viscosity biomaterials.
Claims22
A biomanufacturing system capable of assembling and maturing living tissue in a reduced gravity environment from one or more bioinks comprising:
- a reduced gravity environment;
- a bioprinter, wherein said bioprinter is a three dimensional printer having one or more print heads;
- a cell culturing device having an unoccupied interior, wherein said one or more print heads is in fluid communication with said unoccupied interior within said reduced gravity environment;
- one or more bioinks;
- and
- said reduced gravity environment surrounding said bioprinter and said cell culturing device;
- wherein said one or more print heads print one or more three-dimensional tissues with said one or more bioinks into said unoccupied interior of said cell culturing device, and wherein said cell culturing device incubates said one or more three-dimensional tissues.
4 more elements
An additive manufacturing apparatus comprising:
- a reduced gravity environment;
- one or more cell culturing devices in said reduced gravity environment, wherein said one or more cell culturing devices includes an interior;
- a bioprinter positioned in said reduced gravity environment, wherein said bioprinter has one or more print heads in relation to at least one print stage, wherein said one or more cell culturing devices is positioned proximate said at least one print stage;
- one or more bioinks in fluid communication with said one or more print heads, wherein said one or more bioinks have a viscosity range of about 1 to 10,000,000 centipoise;
- and
- said one or more bioinks in fluid communication with the interior of said one or more cell culturing devices to print one or more tissues and wherein said one or more cell culturing devices incubates said one or more tissues.
3 more elements
Dependencies are inferred from the claim text.