Polymerized peptide and gel having collagen-like structure
AssigneeKola-Gen Pharma, Inc.
InventorsTakaki Koide, Shinichiro Ichise, Shungo Takeuchi, Hiroshi Nose
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AssigneeKola-Gen Pharma, Inc.
InventorsTakaki Koide, Shinichiro Ichise, Shungo Takeuchi, Hiroshi Nose
Estimating the term…
The present invention is produced as a polymerized peptide prepared by oxidatively cross-linking collagen-like peptides having the triple-helical structure containing three peptide chains each containing multiple cysteine (Cys) residues. This polymerized peptide can be processed into a hydrogel and a thin membrane sheet before use, and is capable of imparting a particular physiological function such as cellular adhesion by incorporating functional amino acid sequences present on biological polymers. Further, the present invention provides a method for producing the abovementioned polymerized peptide and the like; and use applications employing the same, such as cell culturing, wound dressing, and compositions including regenerative medical materials and research materials.
A gelling agent comprising at least one kind of a polymerized peptide that has, as a polymerization unit, a triple-chain peptide having a triple-helical structure, and is polymerized by oxidative cross-linking, wherein peptide chains composing the triple-chain peptide are identical to or different from one another, and each peptide chain has:
Dependencies are inferred from the claim text.