Self closing and opening filling needle, needle holder, filler and method

An apparatus comprising:

• a hollow member, a penetrating tip formed at one end of the hollow member configured to penetrate a penetrable septum, at least one port in fluid communication between an interior of the hollow member and an exterior of the hollow member, and a closure, wherein
• (A) one or more of the closure or hollow member is movable relative to the other between (i) a closed position with the closure closing the at least one port and forming a fluid-tight seal between the at least one port and ambient atmosphere to maintain sterility of the at least one port and the interior of the hollow member, and (ii) an open position unsealing the at least one port and allowing substance to flow through the at least one port between said interior and said exterior;
• and
• (B) one or more of the hollow member or septum is movable relative to the other between (i) a first position wherein the penetrating tip is not penetrating the septum, and (ii) a second position wherein the penetrating tip is penetrated through the septum;
• and
• a locking device movable between (i) a locked position locking one or more of the closure or hollow member in the closed position with the closure closing the at least one port, and (ii) an unlocked position allowing movement of one or more of the closure or hollow member relative to the other and into the open position unsealing the at least one port and allowing substance to flow through the at least one port between said interior and said exterior.