Apparatus and method for asepticaly filling pharmaceutical containers with a pharmaceutical fluid using rotary stage

A method for filling pharmaceutical containers with a fluid pharmaceutical product, the method comprising:

• providing an aseptically sealable chamber comprising a robotic arm and a transfer wall capable of having aseptically mounted thereto a plurality of pharmaceutical containers pre-sealed with pierceable closures, wherein the aseptically sealable chamber is capable of maintaining an aseptic condition within an interior of the sealable chamber when the pharmaceutical containers are mounted to the transfer wall,
• aseptically mounting to the transfer wall a plurality of pharmaceutical containers aseptically pre-sealed with corresponding pierceable pharmaceutical container closures, wherein the mounting of the plurality of pharmaceutical containers comprises mounting the plurality of pharmaceutical containers in locations and orientations wherein the corresponding pierceable pharmaceutical container closures are penetrable from within the interior of the sealable chamber, wherein the step of aseptically mounting to the transfer wall a plurality of pharmaceutical containers includes using at least one sealing structure to mount at least one intra-venous bag to the transfer wall, the intra-venous bag includes a tube aseptically sealed to a pierceable closure, and the sealing structure includes two half-annular caps holding the pierceable closure of the intra-venous bag;
• providing within the sealable chamber a first pharmaceutical syringe comprising a first syringe needle,
• aseptically sealing the sealable chamber,
• establishing an aseptic condition within the interior of the sealable chamber and on all portions of the plurality of pharmaceutical containers exposed to the interior of the sealable chamber, and
• transferring a portion of the first fluid pharmaceutical product between the first syringe and at least one of the plurality of pharmaceutical containers through the corresponding pierceable pharmaceutical container closure via the first syringe needle.