Balloon catheters for body lumens

A balloon catheter that is in a gastrointestinal stricture, the balloon catheter comprising:

• an elongated balloon having a main diameter, the elongated balloon comprising at least one neck section, the balloon comprising a first main section and a second main section on opposite sides of the neck section, the balloon comprising a drug coating on the first main section and the neck, wherein the at least one neck section comprises an inflated diameter that is smaller than the main diameter when the balloon is inflated, and when the balloon is inflated the inflated diameter of the neck section comprises an area of reduced compliance relative to the first main section and the second main section;
• wherein the drug coating comprises a therapeutic agent and one or more additives, wherein the therapeutic agent is selected from the group consisting of paclitaxel, a paclitaxel analogue, sirolimus, a sirolimus analogue, everolimus, an everolimus analogue, tacrolimus, a tacrolimus analogue, rapamycin, a mammalian target of rapamycin (mTOR) inhibitor, an mTOR inhibitor analogue, and combinations thereof.