Use of H3K9me3 modulation for enhancing cognitive function
AssigneeThe Regents of the University of California
InventorsCarl W. Cotman, Larry E. Overman, Shikha Snigdha
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Abstract
Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject comprising a therapeutically effective amount of a SUV39H1 inhibitor comprising analogs of ETP69. The therapeutically effective amount is effective in treating cognitive dysfunction in aging and age-related disorders.
Claims15
A composition for reversing cognition loss in an animal subject in need thereof, the composition comprising:
- a therapeutically effective amount of a SUV39H1 inhibitor compound ETP69, and a pharmaceutical cognitive enhancer.
A composition for reversing cognition loss in an animal subject in need thereof, the composition comprising:
- a therapeutically effective amount of an analog of ETP69 compound, and
- a pharmaceutical cognitive enhancer.
Dependencies are inferred from the claim text.