Processes for obtaining purified unsaturated macrocyclic compounds
AssigneeAgan Aroma & fine chemicals Ltd.
InventorsYoulia Hagooly, Alexander Laskavy, Tehila Yosef Gerufi, Eyal Ben-Ari
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Abstract
A process of obtaining a purified geometric isomer of an unsaturated macrocyclic compound is disclosed herein. The process is effected by contacting an ion exchange medium comprising silver ions with a mixture comprising at least one geometric isomer of the unsaturated macrocyclic compound, to thereby obtain at least one fraction comprising the purified geometric isomer of the macrocyclic compound. A system configured for performing the process is also disclosed.
Claims25
A process of obtaining a purified geometric isomer of an unsaturated macrocyclic compound, said unsaturated macrocyclic compound comprising a ring of at least 12 atoms, the process comprising contacting an ion exchange medium comprising silver ions with a mixture comprising at least one geometric isomer of the unsaturated macrocyclic compound, to thereby obtain at least one fraction comprising said purified geometric isomer of said macrocyclic compound, wherein:
- said contacting said ion exchange medium with said mixture is effected at a temperature in a range of from 30° C. to 80° C.;
- and/or
- said contacting said ion exchange medium with said mixture is effected at a first temperature, and the process further comprises eluting said at least one fraction from said ion exchange medium at a second temperature in a range of from 30° C. to 80° C., said second temperature being higher than said first temperature, wherein said unsaturated macrocyclic compound is selected from the group consisting of a cycloalkenone and an oxacycloalkenone.
Dependencies are inferred from the claim text.