Agent for use in the case of fructose intolerance

A method of reducing in a subject at least one of (a) the bioavailability of fructose in the body of said subject, (b) the amount of fructose available to the body of said subject and (c) the amount of fructose available to intestinal bacteria colonizing the intestine of said subject, the subject being a person who would benefit from such reducing, the method comprising administering to the subject an amount of a glucose isomerase sufficient to convert fructose into glucose in said subject, thereby reducing at least one of (a) the bioavailability of fructose in the body of said subject, (b) the amount of fructose available to the body of said subject and (c) the amount of fructose available to intestinal bacteria colonizing in the intestine of said subject.

A method of treating a subject having a condition that is (i) caused by the intake of fructose or fructose containing foodstuffs, or (ii) due to the release of fructose in the digestive tract from other substances, wherein said condition can be treated or ameliorated by the conversion of fructose to glucose in the gastrointestinal tract of said subject by a glucose isomerase, the method comprising administering to said subject in need of such treatment an amount of a glucose isomerase sufficient to effect said conversion, thereby treating said condition that is (i) caused by the intake of fructose or fructose containing foodstuffs, or (ii) due to the release of fructose in the digestive tract from other substances.