# US 10,842,839 B2 · Natural formulation for treating hangover

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- Number: US 10,842,839 B2
- Document ID: US10842839B2
- Status: Granted
- Kind: B2
- Application number: 16/413,523
- Filed: 2019-05-15
- Published: 2019-08-29
- Granted: 2020-11-24
- Earliest claimed: 2016-11-07
- Assignees: Rvrs, LLC
- Applicants: Rvrs, LLC
- Inventors: Nader George Mikhail
- Web page: https://patentgrep.com/patent/US10842839B2

## CPC

- A61K 36/82: Theaceae (Tea family), e.g. camellia
- A61K 9/0095: {Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches (A61K9/0007 takes precedence; eatable gels or foams A61K9/0056; oral mucosa adhesive forms A61K9/006)}
- A61K 31/01: Hydrocarbons
- A61K 31/047: having two or more hydroxy groups, e.g. sorbitol
- A61K 31/07: Retinol compounds, e.g. vitamin A (retinoic acids A61K31/203)
- A61K 31/122: having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K 31/14: Quaternary ammonium compounds, e.g. edrophonium, choline (betaines A61K31/205)
- A61K 31/164: of a carboxylic acid with an aminoalcohol, e.g. ceramides
- A61K 31/197: the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid (carnitine A61K31/205)
- A61K 31/198: Alpha-amino acids, e.g. alanine or edetic acid [EDTA] (betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00)
- A61K 31/355: Tocopherols, e.g. vitamin E
- A61K 31/375: Ascorbic acid, i.e. vitamin C; Salts thereof
- A61K 31/4188: condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
- A61K 31/4415: Pyridoxine, i.e. Vitamin B6 (pyridoxal phosphate A61K31/675)
- A61K 31/455: Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
- A61K 31/51: Thiamines, e.g. vitamin B1
- A61K 31/519: ortho- or peri-condensed with heterocyclic rings
- A61K 31/525: Isoalloxazines, e.g. riboflavins, vitamin B2
- A61K 31/675: having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A61K 31/714: Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
- A61K 31/718: Starch or degraded starch, e.g. amylose, amylopectin
- A61K 33/00: Medicinal preparations containing inorganic active ingredients
- A61K 33/06: Aluminium, calcium or magnesium; Compounds thereof {, e.g. clay}
- A61K 33/08: Oxides; Hydroxides
- A61K 33/30: Zinc; Compounds thereof
- A61K 33/44: Elemental carbon, e.g. charcoal, carbon black
- A61K 36/28: Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K 36/33: Cactaceae (Cactus family), e.g. pricklypear or Cereus
- A61K 36/72: Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K 36/9068: Zingiber, e.g. garden ginger
- A61K 38/063: {Glutathione}
- A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

Compositions and methods for treating and/or preventing hangover are disclosed. In certain embodiments, the compositions include at least one B vitamin, activated charcoal, at least one mineral, and at least one herbal extract.

## Claims

### Claim 1

A composition for treating and/or preventing a hangover, the composition comprising:
an amount of Hovenia dulcis fruit extract in a dosage range of about 10 mg to about 1000 mg per unit dose;
an amount of prickly pear extract in a dosage range of about 50 mg to about 1000 mg per unit dose;
an amount of L-glutathione in a dosage range of about 5 mg to about 100 mg per unit dose; and
an amount of N-acetyl L-cysteine in a dosage range of about 50 mg to about 500 mg per unit dose;
wherein the composition is formulated for oral delivery.

### Claim 2

A composition for treating and/or preventing a hangover, the composition comprising:
amounts of one or more minerals in a dosage range of about 1 mg to about 500 mg per unit dose;
an amount of prickly pear extract in a dosage range of about 50 mg to about 1000 mg per unit dose;
an amount of ginger root extract in a dosage range of about 50 mg to about 1000 mg per unit dose;
an amount of L-glutathione in a dosage range of about 5 mg to about 100 mg per unit dose; and
an amount of N-acetyl L-cysteine in a dosage range of about 50 mg to about 500 mg per unit dose;
wherein the composition is formulated for oral delivery.

### Claim 3

A composition for treating and/or preventing a hangover, the composition comprising:
an amount of milk thistle in a dose range of about 100 mg to about 2000 mg per unit dose;
amounts of one or more minerals in a dosage range of about 1 mg to about 500 mg per unit dose;
amounts of one or more B vitamins in a dosage range of about 0.01 μg to about 100 mg per unit dose; and
an amount of green tea leaf extract in a dosage range of about 10 mg to about 500 mg per unit dose;
an amount of L-glutathione in a dosage range of about 5 mg to about 100 mg per unit dose; and
an amount of N-acetyl L-cysteine in a dosage range of about 50 mg to about 500 mg per unit dose;
wherein the composition is formulated for oral delivery.

### Claim 4 (depends on 1, 2, 3)

The composition of any one of claims 1-3, further comprising:
an amount of activated charcoal in a dosage range of about 1 mg to about 1000 mg per unit dose.

### Claim 5 (depends on 4)

A method for treating and/or preventing a hangover in a subject in need thereof, the method comprising providing to the subject for oral administration the composition of claim 4.

### Claim 6 (depends on 5)

A method of claim 5, wherein the composition is administered orally one, two, three or four doses per day.