Artificial peritoneal tissue and method for producing same

A method for producing an artificial peritoneal tissue comprising a cellular tissue and a mesothelial cell layer that covers a surface of the cellular tissue, wherein the cellular tissue consists of a fibroblast, an extracellular matrix, and at least one of a vascular endothelial cell and a lymphatic endothelial cell forming at least one selected from the group consisting of a vascular network structure and a lymphatic network structure, the method comprising:

• culturing at least one of a vascular endothelial cell and a lymphatic endothelial cell, a fibroblast, and an extracellular matrix, thereby forming the cellular tissue;
• and
• placing a mesothelial cell on the cellular tissue,
• wherein the forming the cellular tissue comprises:
• placing a fibroblast coated with the extracellular matrix;
• and
• placing at least one of a vascular endothelial cell coated with the extracellular matrix and a lymphatic endothelial cell coated with the extracellular matrix, thereby forming the at least one selected from the group consisting of a vascular network structure and a lymphatic network structure,
• wherein adjacent mesothelial cells form cell-cell adhesion in the artificial peritoneal tissue,
• wherein the mesothelial cell layer has a microvillus on a surface thereof,
• wherein the extracellular matrix consists of fibronectin and gelatin, and
• wherein the coated fibroblast and at least one of the coated vascular endothelial cell and the coated lymphatic endothelial cell are stacked on each other.