Systems and methods for MR microscopy analysis of resected tissue
AssigneeCornell University
InventorsDouglas J. Ballon, Brittany Dashevsky, Krishna Juluru, Eric Aronowitz, Henning U. Voss
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Abstract
The present disclosure discusses systems and methods for imaging tissue. The system can reduce the amount of vibrations that are transmitted from a magnetic resonance imaging device to a tissue sample. The system can include a stabilization platform with at least one vibration dampener coupled towards either end of the stabilization platform. A fluid reservoir is coupled to the stabilization platform and a resonator is coupled to the exterior of the fluid reservoir.
Claims20
A system for magnetic resonance imaging of resected tissue comprising:
- a stabilization platform;
- at least one vibration dampener coupled towards each end of the stabilization platform and configured to stabilize the stabilization platform within a bore of a magnetic resonance imaging machine;
- a fluid reservoir coupled to the stabilization platform and configured to contain a fluid and to receive a cassette, the cassette including one or more openings to receive the fluid from within the fluid reservoir;
- one or more shims coupled with sides of the cassette to restrict movement of the cassette within the fluid reservoir during an imaging session;
- and
- a plurality of coils forming a resonator, the resonator coupled to an exterior surface of the fluid reservoir to enable the magnetic resonance imaging machine to acquire images of a tissue sample in the cassette.
A method of imaging tissue, the method comprising
- providing a stabilization system comprising:
- a stabilization platform;
- at least one vibration dampener coupled towards each end of the stabilization platform and configured to stabilize the stabilization platform within a bore of a magnetic resonance imaging machine;
- a fluid reservoir coupled to the stabilization platform and configured to contain a fluid and to receive a cassette, the cassette including one or more openings to receive the fluid from within the fluid reservoir;
- one or more shims coupled with sides of the cassette to restrict movement of the cassette within the fluid reservoir during an imaging session;
- and
- a plurality of coils forming a resonator, the resonator coupled to an exterior surface of the fluid reservoir to enable the magnetic resonance imaging machine to acquire images of a tissue sample in the cassette;
- adding a contrast agent to the fluid reservoir;
- inserting the cassette holding a resected tissue sample into the fluid reservoir;
- and
- acquiring one or more magnetic resonance microscopy images of the resected tissue sample.
Dependencies are inferred from the claim text.