Recombinant E. coli and method of producing Danshensu by using same

A recombinant Escherichia coli (E. coli), wherein the recombinant E. coli simultaneously expresses an α-hydroxycarboxylic acid dehydrogenase and an L-amino acid oxidase,

• wherein the recombinant E. coli expresses any one or more of:
• an exogenous L-glutamate dehydrogenase, an exogenous L-lactate dehydrogenase, a glucose dehydrogenase, and a tyrosine phenol lyase,
• wherein when the recombinant E. coli expresses tyrosine phenol lyase and L-lactate dehydrogenase, the tyrosine phenol lyase and the L-lactate dehydrogenase are simultaneously expressed;
• wherein the α-hydroxycarboxylic acid dehydrogenase is from Lactobacillus plantarum, Enterococcus faecalis, or Lactobacillus fermentum;
• wherein the L-amino acid oxidase is expressed from any one or more of the gene of:
• pmaao from Proteus mirabilis, cmaao from Cosenzaea myxofaciens, praao from Providencia rettgeri, mmaao from Morganella morganii, and ilaao from Ignatzschineria larvae;
• wherein the L-glutamate dehydrogenase is from E. coli, Rhodobacter sphaeroides, Clostridium symbiosum, or Bacillus subtilis;
• wherein the L-lactate dehydrogenase is from Lactococcus lactis;
• wherein the glucose dehydrogenase is from Bacillus subtilis;
• wherein the tyrosine phenol lyase is from Erwinia herbicola;
• and
• wherein the recombinant E. coli comprises a gene knockout of hpaD and mhpB.