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US 10,828,432 B1Granted
Respiratory delivery device and method
AssigneeDe Motu Cordis Pty Ltd
InventorsBrendan O'Flaherty, Johann Lipman, Patrick Joseph Lynch
Life of this patent
Estimating the term…
Abstract
The present invention provides for a particulate delivery device capable of facilitating both respiratory delivery of compositions under negative pressure and positive pressure. The device comprises an actuator, movable by negative pressure or positive pressure, to allow for gas flow through the device and simultaneously assist with delivery of the particulate into a vortex chamber prior to delivery to the airway of a subject.
Claims21
A device for delivery of a composition to an airway of a subject, the device comprising, in fluid communication:
- a gas inlet;
- a gas outlet;
- an actuator having an upper surface and a lower surface;
- a composition receptacle, adapted to receive the composition;
- and
- a dispersion chamber,
- wherein the actuator is configured to be moveable between:
- (a) a first configuration wherein the lower surface of the actuator is seated adjacent the gas inlet to restrict gas flow entering the device and wherein the upper surface of the actuator is adjacent to a lower extent of the composition receptacle to allow the composition to be located in the composition receptacle;
- and
- (b) a second configuration wherein the lower surface of the actuator is displaced in the direction of the gas outlet, compared with the first configuration, to open a gas flow path into the device through the gas inlet and wherein the upper surface of the actuator is closer to an upper extent of the composition receptacle than the lower extent of the composition receptacle to displace the composition into the dispersion chamber;
- and
- wherein the actuator is configured to be moveable between the first configuration and the second configuration via each of:
- (i) application of positive pressure via the gas inlet;
- and (ii) application of negative pressure via the gas outlet.
11 more elements
A device for delivery of a composition to an airway of a subject, the device comprising, in fluid communication:
- a gas inlet;
- a gas outlet;
- a floating piston actuator having an upper surface and a lower surface;
- a composition receptacle adapted to receive the composition;
- a dispersion chamber located between the composition receptacle and the gas outlet;
- and
- one or more chamber ports forming a gas flow pathway between the gas inlet and the dispersion chamber,
- wherein the floating piston actuator is configured to be moveable between:
- (a) a first configuration wherein the lower surface of the floating piston actuator is seated adjacent the gas inlet to restrict gas flow entering the one or more chamber ports and wherein the upper surface of the actuator is adjacent to a lower extent of the composition receptacle to allow the composition to be located in the composition receptacle;
- and
- (b) a second configuration wherein the lower surface of the floating piston actuator is displaced in the direction of the gas outlet, compared with the first configuration, to open a gas flow path through the one or more chamber ports and wherein the upper surface of the actuator is closer to an upper extent of the composition receptacle than the lower extent of the composition receptacle to displace the composition into the dispersion chamber;
- and
- wherein the actuator is configured to be moveable between the first configuration and the second configuration via each of:
- (i) application of positive pressure via the gas inlet;
- and (ii) application of negative pressure via the gas outlet.
12 more elements
A device for delivery of a composition to an airway of a subject, the device comprising, in fluid communication:
- a gas inlet located at a first end of the device, to allow a gas to enter the device, and having a lip or flange on an inner surface thereof;
- a gas outlet located at a second end of the device, opposite the first end;
- a floating piston actuator having an upper surface and a lower surface;
- a composition receptacle adapted to receive the composition;
- a dispersion chamber located between the composition receptacle and the gas outlet;
- one or more chamber ports forming a non-linear gas flow pathway between the gas inlet and the dispersion chamber;
- and
- a deagglomerator located between an upper extent of the dispersion chamber and the gas outlet,
- wherein the floating piston actuator is configured to be moveable between:
- (a) a first configuration wherein the lower surface of the floating piston actuator is sealingly seated on the lip or flange of the gas inlet to restrict gas flow entering the one or more chamber ports and wherein the upper surface of the actuator is adjacent a lower extent of the composition receptacle to allow the composition to be located in the composition receptacle;
- and
- (b) a second configuration wherein the lower surface of the floating piston actuator is displaced in the direction of the gas outlet, compared with the first configuration, to open a gas flow path through the one or more chamber ports and wherein the upper surface of the actuator is closer to an upper extent of the composition receptacle than the lower extent of the composition receptacle to displace the composition into the dispersion chamber;
- and
- wherein the actuator is configured to be moveable between the first configuration and the second configuration via each of;
- (i) application of positive pressure via the gas inlet;
- and (ii) application of negative pressure via the gas outlet.
13 more elements
Dependencies are inferred from the claim text.