Compounds that modulate fatty acid receptor activity and pet food products containing the same
AssigneeMars, Incorporated
InventorsScott Joseph McGrane, Matthew Ronald Gibbs, Richard Masten Fine, Jerry Wallace Skiles
Life of this patent
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Abstract
A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a GPR120 fatty acid receptor that can be used to enhance the fatty acid taste and/or palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.
Claims8
A flavor composition for a cat food product comprising a compound of Formula II:
- wherein
- X is (C)R1R2, O, S, C(O), or a chemical bond;
- X1 is (C)R1R2, O, S, or N(R1);
- Y is COOH, SO3H, —OP(O)(OH)2, or Tetrazole;
- W is halogen, COOH, COOMe, CN, N(R1)(R2), CHO, CONR1R2, Aryl, OH, H, —S-Aryl, —O-Aryl, —N-Aryl, CF3, OCH3, CH3, NO2, or OEt;
- Z1 and Z2 are each independently selected from halogen, COOH, COOMe, CN, N(R1)(R2), CHO, CONR1R2, Aryl, OH, H, —S-Aryl, —O-Aryl, —N-Aryl, CF3, OCH3, CH3, NO2, and OEt;
- R1 and R2 are each independently selected from H and branched or unbranched C1-C6 lower alkyl;
- n1 is 0-4;
- n2 is 0-2;
- and
- n3 is 0-4,
- wherein the compound is present in the flavor composition at a concentration of from about 0.001 μM to about 1 mM, wherein the compound is a feline GPR 120 agonist, and wherein the compound increases a fatty acid taste of the cat food product.
A method of increasing a fatty acid taste intensity in a cat food product comprising admixing a cat food product with a flavor composition comprising a compound represented by Formula II:
- wherein
- X is (C)R1R2, O, S, C(O), or a chemical bond;
- X1 is (C)R1R2, O, S, or N(R1);
- Y is COOH, SO3H, —OP(O)(OH)2, or Tetrazole;
- W is halogen, COOH, COOMe, CN, N(R1)(R2), CHO, CONR1R2, Aryl, OH, H, —S-Aryl, —O-Aryl, —N-Aryl, CF3, OCH3, CH3, NO2, or OEt;
- Z1 and Z2 are each independently selected from halogen, COOH, COOMe, CN, N(R1)(R2), CHO, CONR1R2, Aryl, OH, H, —S-Aryl, —O-Aryl, —N-Aryl, CF3, OCH3, CH3, NO2, and OEt;
- R1 and R2 are each independently selected from H and branched or unbranched C1-C6 lower alkyl;
- n1 is 0-4;
- n2 is 0-2;
- and
- n3 is 0-4;
- wherein the compound is present in the flavor composition at a concentration of from about 0.001 μM to about 1mM, wherein the compound is a feline GPR 120 agonist, and wherein the compound increases a fatty acid taste of the cat food product.
Dependencies are inferred from the claim text.