System for high pressure, high shear processing of fluids
AssigneePressure Biosciences, Inc.
InventorEdmund Y. Ting
Life of this patent
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Abstract
A method for high fluid shear processing of a fluid uses an isolator that has a first sub-chamber for containing a first fluid and a second sub-chamber for containing a second fluid defined by a separator positioned in the chamber and movable between a first end of the chamber and a second end of the chamber. The two sub-chambers are in pressure communication with each other but are not in fluid communication with each other. A first fluid is pumped at an ultrahigh pressure into the first-sub chamber, and the pressure in the first sub-chamber causes a second fluid to be processed to be discharged from the second sub-chamber into a processing valve. A system is also provided for performing the steps of this method.
Claims18
A method of high pressure, high shear processing of a fluid, the method comprising the steps of:
- providing at least one isolator for selectively containing and discharging a second fluid, the at least one isolator further including
- an isolator wall defining a chamber,
- a separator positioned in the chamber and movable between a first end of the chamber and a second end of the chamber, the separator engaging the isolator wall to further divide the chamber into a first sub-chamber and a second sub-chamber that are in pressure communication with each other but are not in fluid communication with each other,
- a first sub-chamber inlet valve in fluid communication with an ultrahigh pressure pump and the first sub-chamber,
- a first sub-chamber outlet valve in fluid communication with the first sub-chamber,
- a first check valve in fluid communication with the second sub-chamber to allow fluid to enter the second sub-chamber, and
- a second check valve in fluid communication with the second sub-chamber to exhaust fluid from the second sub-chamber;
- providing a processing unit in fluid communication with the second check valve of the at least one isolator;
- alternately directing a first fluid at a pressure of at least 20,000 psi into the first sub-chamber and directing the second fluid into the second sub-chamber, wherein directing the first fluid into the first sub-chamber causes the second fluid to be discharged from the second sub-chamber, through the second check valve, and through the processing unit;
- and
- controlling a temperature of the second fluid when it is in a manifold that is in fluid communication with the second check valve.
A high fluid shear processing system comprising:
- an ultrahigh pressure pump capable of advancing a first fluid at a pressure of at least 20,000 psi;
- and
- at least one isolator for selectively containing and discharging a second fluid, the at least one isolator including
- an isolator wall defining a chamber,
- a separator positioned in the chamber and movable between a first end of the chamber and a second end of the chamber, the separator engaging the isolator wall to further divide the chamber into a first sub-chamber and a second sub-chamber that are in pressure communication with each other but are not in fluid communication with each other,
- a first sub-chamber inlet valve in fluid communication with the ultrahigh pressure pump and the first sub-chamber,
- a first sub-chamber outlet valve in fluid communication with the first sub-chamber,
- a first check valve in fluid communication with the second sub-chamber to allow fluid to enter the second sub-chamber, and
- a second check valve in fluid communication with the second sub-chamber to exhaust fluid from the second sub-chamber;
- and
- a processing unit in fluid communication with the second check valve, wherein the processing unit is a homogenizing valve.
Dependencies are inferred from the claim text.