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US 10,808,219 B2Granted
Systems and methods for particle analysis
AssigneeDeepcell, Inc.
InventorsMahdokht Masaeli, Mahyar Salek, Hou-Pu Chou, Soroush Kahkeshani
Life of this patent
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Abstract
The present disclosure provides systems and methods for sorting a cell. The system may comprise a flow channel configured to transport a cell through the channel. The system may comprise an imaging device configured to capture an image of the cell from a plurality of different angles as the cell is transported through the flow channel. The system may comprise a processor configured to analyze the image using a deep learning algorithm to enable sorting of the cell.
Claims24
A computer-implemented method for classifying a cell, comprising:
- (a) providing a plurality of images of the cell, wherein the plurality of images is captured from a plurality of different angles while the cell is being suspended in a fluid and transported through a flow channel;
- (b) processing the plurality of images of the cell using a deep learning algorithm to classify the cell in each of the plurality of images of the cell, thereby generating a plurality of initial cell classifications of the cell, wherein each initial cell classification of the plurality of initial cell classifications of the cell comprises an indicator associated with a characteristic or a disease state of the cell;
- and
- (c) aggregating the plurality of initial cell classifications of the cell to determine a final classification of the cell.
1 more element
Dependencies are inferred from the claim text.