Rexinoid compounds and methods of using rexinoid compounds for treating metabolic disorders and cancer
AssigneeThe UAB Research Foundation
InventorsDonald D. Muccio, Venkatram Reddy Atigadda, Wayne J. Brouillette, Clinton J. Grubbs, Jeonga Kim
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Abstract
Novel rexinoid compounds are provided herein. Also provided herein are methods of using the compounds to treat disorders, such as metabolic disorders, diabetes, insulin resistance, glucose intolerance, obesity, steatosis, inflammation, and/or cancer.
Claims8
A method of ameliorating diabetes, dyslipidemia, insulin resistance, glucose intolerance, obesity, or steatosis in a subject, comprising administering to a subject an effective amount of a compound of the following formula:
- or a pharmaceutically acceptable salt thereof.
A method of ameliorating breast cancer in a subject, comprising administering to a subject an effective amount of a compound of the following formula:
- or a pharmaceutically acceptable salt thereof.
A compound having the following formula:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.