US 10,799,477 B2 · Pharmaceutical composition for preventing or treating LDL cholesterol-related diseases, containing ribosome-binding preparation

Abstract

The present invention relates to: a pharmaceutical composition for preventing or treating LDL cholesterol-related diseases, containing a ribosome-binding preparation; a food composition; and a method for preventing or treating LDL cholesterol-related diseases by using the composition. According to the present invention, the ribosome-binding preparation selectively increases the expression of an LDL receptor in intestinal epithelial cells so as to promote LDL absorption in blood and tissue, such that LDL level in the blood can be reduced, thereby being useful for preventing or treating various LDL cholesterol-related diseases including LDL hypercholesterolemia, hyperlipidemia, hypertension and apoplexy.

Claims3

Dependent claims

A method for treatment of a Low-Density Lipoprotein cholesterol-related disease, comprising administering a composition comprising deoxynivalenol to a subject in need thereof, wherein the Low-Density Lipoprotein cholesterol-related disease comprises at least one selected from the group consisting of Hyperlipidemia, Hypercholesterolemia, and Hyper Low-Density Lipoprotein Cholesterinosis.

Dependencies are inferred from the claim text.

Facts

Application

16/306,466Filed 1 Jun 2017

Priority

KR 10-2016-00683061 Jun 2016

Published

US 2019/0183858 A120 Jun 2019

Granted

13 Oct 2020

Term ends

Not estimatedThe source records don’t support an estimate.

Classification26 codes

A61K 31/4015
Having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil: having oxo groups…
A23L 33/10
Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof: using additives
A61K 9/0053
Galenical forms characterised by the site of application: mouth and digestive tract, i.e. intraoral and peroral administration
A61K 31/336
Having oxygen as the only ring hetero atom, e.g. fungichromin: having three-membered rings, e.g. oxirane, fumagillin

Pharmaceutical composition for preventing or treating LDL cholesterol-related diseases, containing ribosome-binding preparation

Life of this patent

Pharmaceutical composition for preventing or treating LDL cholesterol-related diseases, containing ribosome-binding preparation

Life of this patent

Abstract

Claims3