Nucleic acid molecule encoding glei protein variant with increased phytic acid sensitivity and use thereof

A non-natural synthetic nucleic acid molecule comprising a nucleotide sequence having at least 90% identity to the nucleotide sequence of SEQ ID NO:

• 1 and which encodes plant Gle1 protein variant:
• wherein said plant Gle1 protein variant comprises a phytic acid-binding pocket represented by SEQ ID NO:
• 18,
• wherein the eighth amino acid residue of SEQ ID NO:
• 18 is substituted with a basic amino acid residue and the fourth amino acid residue of SEQ ID NO:
• 18 is selected from Glu and a basic amino acid residue, and wherein transgenic expression of said nucleotide sequence encoding said plant Gle1 protein in a transgenic plant increases seed yield, seed germination, plant growth or abiotic stress tolerance as compared to a control plant of the same plant species grown under identical conditions and lacking said non-natural synthetic nucleic acid molecule.