Methods and compositions for production of aromatic and other compounds in yeast
AssigneeIowa State University Research Foundation, Inc.
InventorsZengyi Shao, Mingfeng Cao, Miguel Suastegui, Meirong Gao
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Abstract
The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
Claims15
A vector for gene expression or gene editing in yeast comprising:
- a nucleic acid sequence one SEQ ID NO:
- 5 (CEN 5);
- and one or more regulatory elements functional in a yeast cell, wherein the vector is an episomal vector.
Dependencies are inferred from the claim text.