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US 10,786,601 B2Granted
Composition comprising hyaluronic acid and mepivacaine
AssigneeTeoxane
InventorsFrancois Bourdon, Stephane Meunier
Life of this patent
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AssigneeTeoxane
InventorsFrancois Bourdon, Stephane Meunier
Estimating the term…
Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
A stable, sterile, injectable composition having an effective amount of cross-linked hyaluronic acid or a salt thereof, and mepivacaine or a salt thereof at a concentration ranging from 0.05 to 3 wt % of an overall weight of the stable, sterile, injectable composition, prepared by a process comprising:
A method of preparing a stable, sterile, injectable composition having an effective amount of cross-linked hyaluronic acid or a salt thereof, and mepivacaine or a salt thereof at a concentration ranging from 0.05 to 3 wt % of an overall weight of the stable, sterile, injectable composition, the method comprising:
Dependencies are inferred from the claim text.